Directrices españolas basadas en la evidencia para el tratamiento de la psoriasis con agentes biológicos, 2013

Biologic therapy is a well-established strategy for managing moderate and severe psoriasis. Nevertheless, the high cost of such therapy, the relatively short span of clinical experience with biologics, and the abundance of literature now available on these agents have made evidence-based and consens...

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Autores: Puig Sanz, Lluís|||0000-0001-6083-0952, Carrascosa, José Manuel|||0000-0003-4266-0771, Carretero, Gregorio|||0000-0002-2469-3417, De la Cueva, Pablo|||0000-0003-4807-3551, Lafuente-Urrez, Rosario Fátima|||0000-0003-3107-315X, Belinchón, Isabel|||0000-0002-6007-7320, Sánchez-Regaña, Manuel L.|||0000-0001-9356-9471, García-Bustínduy, Marta C.|||0000-0003-3105-811X, Ribera Pibernat, Miguel|||0000-0002-5151-3338, Alsina, Mercè, Ferrándiz, Carlos|||0000-0001-9030-8399, Fonseca, Eduardo|||0000-0002-8048-2681, García-Patos Briones, Vicente|||0000-0003-1654-6035, Herrera-Ceballos, Enrique, López-Estebaranz, José Luis, Marrón, Servando E.|||0000-0001-5632-0351, Moreno, José Carlos, Notario, Jaime|||0000-0001-9676-6147, Rivera, Raquel|||0000-0002-4604-0724, Rodriguez-Cerdeira, Carmen|||0000-0001-9939-0771, Romero, Antonio Rosas, Ruíz Villaverde, Ricardo|||0000-0002-0381-6174, Taberner, Rosa|||0000-0002-8339-8186, Vidal, David R.
Tipo de recurso: artículo
Fecha de publicación:2013
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:español
OAI Identifier:oai:ddd.uab.cat:303806
Acceso en línea:https://ddd.uab.cat/record/303806
https://dx.doi.org/urn:doi:10.1016/j.adengl.2013.04.013
Access Level:acceso abierto
Palabra clave:Adalimumab
Biológicos
Etanercept
Guía
Infliximab
Psoriasis
Terapia biológica
Tratamiento
Ustekinumab
Descripción
Sumario:Biologic therapy is a well-established strategy for managing moderate and severe psoriasis. Nevertheless, the high cost of such therapy, the relatively short span of clinical experience with biologics, and the abundance of literature now available on these agents have made evidence-based and consensus-based clinical guidelines necessary. The ideal goal of psoriasis treatment is to achieve complete or nearly complete clearing of lesions and to maintain it over time. Failing that ideal, the goal would be to reduce involvement to localized lesions that can be controlled with topical therapy. Although current evidence allows us to directly or indirectly compare the efficacy or risk of primary or secondary failure of available biologics based on objective outcomes, clinical trial findings cannot be directly translated to routine practice. As a result, the prescribing physician must tailor the treatment regimen to the individual patient. This update of the clinical practice guidelines issued by the Spanish Academy of Dermatology and Venereology (AEDV) on biologic therapy for psoriasis incorporates information from the most recent publications on this topic. © 2011 Elsevier España, S.L. and AEDV. All rights reserved.