EHealth intervention for quality of life in long-term breast cancer survivors: randomized controlled trial
Background: Digital health interventions have shown promise for improving quality of life, especially in the short term after treatment. However, evidence regarding long-term breast cancer survivors (LT-BCSs; disease free >5 years) remains limited. This study aimed to evaluate the effectivene...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2026 |
| País: | España |
| Institución: | Universidad Pública de Navarra |
| Repositorio: | Academica-e. Repositorio Institucional de la Universidad Pública de Navarra |
| OAI Identifier: | oai:dnet:academicae__::3217319513ebb6823f6bafdba270d49b |
| Acceso en línea: | https://hdl.handle.net/2454/56800 |
| Access Level: | acceso abierto |
| Palabra clave: | Breast cancer Long-term care Quality of life Survivorship EHealth |
| Sumario: | Background: Digital health interventions have shown promise for improving quality of life, especially in the short term after treatment. However, evidence regarding long-term breast cancer survivors (LT-BCSs; disease free >5 years) remains limited. This study aimed to evaluate the effectiveness of an eHealth intervention targeting health promotion and late sequelae management to improve LT-BCSs’ quality of life. Methods: In a randomized controlled clinical trial, 201 LT-BCSs (mean ¼ 11 years posttreatment) were randomly assigned to an intervention group (n ¼ 102) using the CUMACA-M mobile application with specific health advice and recommendations for LT-BCSs, or a control group (n ¼ 99) receiving usual care. Quality of life was measured with the Quality of Life–Cancer Survivors (QOL-CS) scale at baseline and after 3months. Analyses followed an intention-to-treat approach using t tests, nonparametric tests, and effect sizes. Results: At 3 months, no statistically or clinically significant differences between the groups in the overall quality of life score (QOL-CS) were found (difference-in-differences ¼ 0.11; 95% confidence interval ¼ −0.10 to 0.32; P ¼ .303). In the intervention group, a small intragroup decrease in spiritual well-being was observed (−0.25; −0.49 to −0.02), of uncertain clinical significance; no significant differences between groups were detected. Conclusions: This eHealth intervention did not improve the quality of life of LT-BCSs, suggesting that more personalized, interactive, or professionally supported strategies may be needed. Future research should evaluate the long-term outcomes and effectiveness of hybrid or personalized digital strategies in this population. Trial Registration: ClinicalTrials.gov NCT05322460; |
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