Iridium oxide (IV) nanoparticle-based lateral flow immunoassay

Lateral flow biosensors are paper-based devices that allow the detection of different types of analytes with quickness, robustness and selectivity, without leaving behind paper sensors benefits as low-cost, recyclability and sustainability. Nanomaterials have been widely reported in lateral flow bio...

Descripción completa

Detalles Bibliográficos
Autores: Quesada-González, Daniel|||0000-0003-3064-2146, Sena-Torralba, Amadeo|||0000-0003-1340-1383, Wicaksono, Wiyogo Prio, De La Escosura-Muñiz, Alfredo|||0000-0002-9600-0253, Ivandini, Tribidasari A., Merkoçi, Arben|||0000-0003-2486-8085
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:218087
Acceso en línea:https://ddd.uab.cat/record/218087
https://dx.doi.org/urn:doi:10.1016/j.bios.2019.02.049
Access Level:acceso abierto
Palabra clave:Iridium oxide nanoparticles
Lateral flow immunoassay
Paper-based biosensor
Mobile phone sensing
Descripción
Sumario:Lateral flow biosensors are paper-based devices that allow the detection of different types of analytes with quickness, robustness and selectivity, without leaving behind paper sensors benefits as low-cost, recyclability and sustainability. Nanomaterials have been widely reported in lateral flow biosensors, offering new sensing strategies based on optical or electrical detection techniques. Looking for other advantageous nanomaterials, we propose for the first time the use of iridium oxide (IV) nanoparticles in lateral flow assays for the detection of human immunoglobulin as a model protein. These nanoparticles can be easily prepared and conjugated with biomarkers. Their dark blue color gives a high contrast against the white background of the strips being in this way excellent labels.