Cofactors of wheat-dependent exercise-induced anaphylaxis do not increase highly individual gliadin absorption in healthy volunteers

[Background] In wheat-dependent exercise-induced anaphylaxis (WDEIA), cofactors such as exercise, acetylsalicylic acid (ASA), alcohol or unfavorable climatic conditions are required to elicit a reaction to wheat products. The mechanism of action of these cofactors is unknown, but an increase of glia...

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Detalles Bibliográficos
Autores: Scherf, Katharina A., Lindenau, Ann-Christin, Valentini, Luzia, Collado, María Carmen, García Mantrana, Izaskun, Christensen, Morten, Tomsitz, Dirk, Kugler, Claudia, Biedermann, Tilo, Brockow, Knut
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/178966
Acceso en línea:http://hdl.handle.net/10261/178966
Access Level:acceso abierto
Palabra clave:Cofactor
Gliadin
Gluten
Gut microbiota
Intestinal permeability
Wheat allergy
Wheat-dependent exercise induced anaphylaxis (WDEIA)
Zonulin
Descripción
Sumario:[Background] In wheat-dependent exercise-induced anaphylaxis (WDEIA), cofactors such as exercise, acetylsalicylic acid (ASA), alcohol or unfavorable climatic conditions are required to elicit a reaction to wheat products. The mechanism of action of these cofactors is unknown, but an increase of gliadin absorption has been speculated. Our objectives were to study gliadin absorption with and without cofactors and to correlate plasma gliadin levels with factors influencing protein absorption in healthy volunteers.

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