SARS-CoV-2 antibodies, serum inflammatory biomarkers and clinical severity of hospitalized COVID-19 patients

[Background] The involvement of SARS-CoV-2 antibodies in mediating immunopathogenetic events in COVID-19 patients has been suggested. By using several experimental approaches, we investigated the potential association between SARS-CoV-2 IgGs recognizing the spike (S) protein receptor-binding domain...

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Detalles Bibliográficos
Autores: Gozalbo-Rovira, Roberto, Giménez, Estela, Latorre, Victor, Francés-Gómez, Clara, Albert, Eliseo, Buesa, Javier, Marina, Alberto, Blasco, María Luisa, Signes-Costa, Jaime, Rodríguez-Díaz, Jesús, Geller, Ron, Navarro, David
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/219588
Acceso en línea:http://hdl.handle.net/10261/219588
Access Level:acceso abierto
Palabra clave:SARS-CoV-2
COVID-19
Neutralizing antibodies
Inflammatory biomarkers
Descripción
Sumario:[Background] The involvement of SARS-CoV-2 antibodies in mediating immunopathogenetic events in COVID-19 patients has been suggested. By using several experimental approaches, we investigated the potential association between SARS-CoV-2 IgGs recognizing the spike (S) protein receptor-binding domain (RBD), neutralizing antibodies (NtAb) targeting S, and COVID-19 severity.

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