Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus)

10 pages, 4 figures, 1 table, supporting information http://g3journal.org/content/4/10/1871/suppl/DC1

Detalles Bibliográficos
Autores: Taboada, Xoana, Hermida, Miguel, Pardo, Belén G., Vera, Manuel, Piferrer, Francesc, Viñas, Ana, Bouza, Carmen, Martínez, Paulino
Tipo de recurso: artículo
Fecha de publicación:2014
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/108808
Acceso en línea:http://hdl.handle.net/10261/108808
Access Level:acceso abierto
Palabra clave:Determination
Genetics of sex
Evolution of sex
Differentiation
Sex genetic
Turbot
Sex determining
Master gene
Comparative
Mapping
id ES_fa74c250bce006331e582389a2e8b0d9
oai_identifier_str oai:digital.csic.es:10261/108808
network_acronym_str ES
network_name_str España
repository_id_str
spelling Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus)Taboada, XoanaHermida, MiguelPardo, Belén G.Vera, ManuelPiferrer, FrancescViñas, AnaBouza, CarmenMartínez, PaulinoDeterminationGenetics of sexEvolution of sexDifferentiationSex geneticTurbotSex determiningMaster geneComparativeMapping10 pages, 4 figures, 1 table, supporting information http://g3journal.org/content/4/10/1871/suppl/DC1Fish sex determination (SD) systems are varied, suggesting evolutionary changes including either multiple evolution origins of genetic SD from nongenetic systems (such as environmental SD) and/or turnover events replacing one genetic system by another. When genetic SD is found, cytological differentiation between the two members of the sex chromosome pair is often minor or undetectable. The turbot (Scophthalmus maximus), a valuable commercial flatfish, has a ZZ/ZW system and a major SD region on linkage group 5 (LG5), but there are also other minor genetic and environmental influences. We here report refined mapping of the turbot SD region, supported by comparative mapping with model fish species, to identify the turbot master SD gene. Six genes were located to the SD region, two of them associated with gonad development (sox2 and dnajc19). All showed a high association with sex within families (P = 0), but not at the population level, so they are probably partially sex-linked genes, but not SD gene itself. Analysis of crossovers in LG5 using two families confirmed a ZZ/ZW system in turbot and suggested a revised map position for the master gene. Genetic diversity and differentiation for 25 LG5 genetic markers showed no differences between males and females sampled from a wild population, suggesting a recent origin of the SD region in turbot. We also analyzed associations with markers of the most relevant sex-related linkage groups in brill (S. rhombus), a closely related species to turbot; the data suggest that an ancient XX/XY system in brill changed to a ZZ/ZW mechanism in turbot. © 2014 Taboada et al.This research work was supported by the Consellería de Educación e Ordenación Universitaria and the Dirección Xeral de I+D Xunta de Galicia (project 10MMA200027PR) and by the Spanish Government (Consolider Ingenio Aquagenomics: CSD2007-00002 project) and Spanish Ministerio de Ciencia e Innovación (AGL2009-13273) projectsPeer ReviewedGenetics Society of America2014201420142014info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://hdl.handle.net/10261/108808reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.1534/g3.114.012328info:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1088082026-05-22T06:33:51Z
dc.title.none.fl_str_mv Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus)
title Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus)
spellingShingle Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus)
Taboada, Xoana
Determination
Genetics of sex
Evolution of sex
Differentiation
Sex genetic
Turbot
Sex determining
Master gene
Comparative
Mapping
title_short Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus)
title_full Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus)
title_fullStr Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus)
title_full_unstemmed Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus)
title_sort Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus)
dc.creator.none.fl_str_mv Taboada, Xoana
Hermida, Miguel
Pardo, Belén G.
Vera, Manuel
Piferrer, Francesc
Viñas, Ana
Bouza, Carmen
Martínez, Paulino
author Taboada, Xoana
author_facet Taboada, Xoana
Hermida, Miguel
Pardo, Belén G.
Vera, Manuel
Piferrer, Francesc
Viñas, Ana
Bouza, Carmen
Martínez, Paulino
author_role author
author2 Hermida, Miguel
Pardo, Belén G.
Vera, Manuel
Piferrer, Francesc
Viñas, Ana
Bouza, Carmen
Martínez, Paulino
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Determination
Genetics of sex
Evolution of sex
Differentiation
Sex genetic
Turbot
Sex determining
Master gene
Comparative
Mapping
topic Determination
Genetics of sex
Evolution of sex
Differentiation
Sex genetic
Turbot
Sex determining
Master gene
Comparative
Mapping
description 10 pages, 4 figures, 1 table, supporting information http://g3journal.org/content/4/10/1871/suppl/DC1
publishDate 2014
dc.date.none.fl_str_mv 2014
2014
2014
2014
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/108808
url http://hdl.handle.net/10261/108808
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.1534/g3.114.012328
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Genetics Society of America
publisher.none.fl_str_mv Genetics Society of America
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869425213007986688
score 15.811543

Similares en LA Referencia