Nucleus accumbens functional connectivity and circulating endocannabinoids levels in anorexia nervosa

Introduction: Neuroimaging findings have reported aberrant functional connectivity in brain regions involved reward system in individuals with anorexia nervosa (AN) altering hedonic processing over food. Likewise, endocannabinoids such as Anandamide (AEA) and 2-Arachidonoylglycerol (2-AG) have been...

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Detalhes bibliográficos
Autores: Miranda Olivos, Romina, Baenas, Isabel, Pastor, A., Alonso Ortega, María del Pino, Codina, E., Sánchez Zaplana, Isabel, Juaneda Seguí, Asier, Jiménez-Murcia, Susana, De La Torre, R., Soriano Mas, Carles, Fernández Aranda, Fernando
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Recursos:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/211241
Acesso em linha:https://hdl.handle.net/2445/211241
Access Level:acceso abierto
Palavra-chave:Anorèxia nerviosa
Neurones
Lípids
Anorexia nervosa
Neurons
Lipids
Descrição
Resumo:Introduction: Neuroimaging findings have reported aberrant functional connectivity in brain regions involved reward system in individuals with anorexia nervosa (AN) altering hedonic processing over food. Likewise, endocannabinoids such as Anandamide (AEA) and 2-Arachidonoylglycerol (2-AG) have been involved in rewarding aspects of food intake. Objectives: To identify nucleus accumbens (NAcc) functional connectivity with whole-brain comparing between individuals with AN and controls. Furthermore, in a sub-study, to explore the interaction between NAcc functional connectivity and peripheral AEA and 2-AG levels.

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