Prevalence, Abundance, and Virulence of Adherent-Invasive Escherichia coli in Ulcerative Colitis, Colorectal Cancer, and Coeliac Disease

Adherent-invasive E. coli (AIEC) has largely been implicated in the pathogenesis of Crohn's disease (CD). E. coli strains with similar genetic backgrounds and virulence genes profiles have been associated with other intestinal disorders, such as ulcerative colitis (UC), colorectal cancer (CRC),...

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Detalles Bibliográficos
Autores: López Siles, Mireia, Camprubí Font, Carla, Gómez del Pulgar, Eva M., Sabat Mir, Miriam, Busquets, David, Sanz Herranz, Yolanda, Martínez Medina, Margarita
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/268047
Acceso en línea:http://hdl.handle.net/10261/268047
https://api.elsevier.com/content/abstract/scopus_id/85127398569
Access Level:acceso abierto
Palabra clave:Crohn’s disease
Adherent-invasive Escherichia coli
Coeliac disease
Colorectal cancer
Ulcerative colitis
Descripción
Sumario:Adherent-invasive E. coli (AIEC) has largely been implicated in the pathogenesis of Crohn's disease (CD). E. coli strains with similar genetic backgrounds and virulence genes profiles have been associated with other intestinal disorders, such as ulcerative colitis (UC), colorectal cancer (CRC), and coeliac disease (CeD), but the role of AIEC in these diseases remains unexplored. We aimed to assess the distribution, abundance, and pathogenic features of AIEC in UC, CRC, and CeD.