Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films

A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical,...

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Autores: Figueiredo, Andrea G. P. R., Figueiredo, Ana R. P., Alonso Varona, Ana Isabel, De Matos Fernandes, Susana, Palomares Casado, Teodoro, Rubio Azpeitia, Eva, Barros-Timmons, Ana, Silvestre, Armando J. D., Neto, Carlos Pascoal, Freire, Carmen S. R.
Tipo de recurso: artículo
Fecha de publicación:2013
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/11289
Acceso en línea:http://hdl.handle.net/10810/11289
Access Level:acceso abierto
Palabra clave:cellulose
hydrogels
composites
scaffolds
diffusion
delivery
phema
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spelling Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite FilmsFigueiredo, Andrea G. P. R.Figueiredo, Ana R. P.Alonso Varona, Ana IsabelDe Matos Fernandes, SusanaPalomares Casado, TeodoroRubio Azpeitia, EvaBarros-Timmons, AnaSilvestre, Armando J. D.Neto, Carlos PascoalFreire, Carmen S. R.cellulosehydrogelscompositesscaffoldsdiffusiondeliveryphemaA series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.Andrea G. P. R. Figueiredo and Susana C. M. Fernandes thank the Fundacao para a Ciencia e Tecnologia (Portugal) for their Scientific Research Grants (SFRH/BPD/63219/2009 and SFRH/BPD/70119/2010, resp.), cofinancing by POPH/ESF Program. The authors thank CICECO (Pest-C/CTM/LA0011/2013) and FCT for funding within the scope of the "National Program for Scientific reequipment," Rede/1509/RME/2005, REEQ/515/CTM/2005, and University of the Basque Country for financial support (UPV/EHU, Project GIU 10/16). The authors also acknowledge the technical and human support of General Research Services (SGIker) from the UPV/EHU for the SEM analysis.Hindawi Publishing Corporation201420142013info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10810/11289reponame:Addi. Archivo Digital para la Docencia y la Investigacióninstname:Universidad del País VascoIngléshttp://www.hindawi.com/journals/bmri/2013/698141/info:eu-repo/semantics/openAccessCopyright © 2013 Andrea G. P. R. Figueiredo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.oai:addi.ehu.eus:10810/112892026-06-18T09:23:17Z
dc.title.none.fl_str_mv Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
title Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
spellingShingle Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
Figueiredo, Andrea G. P. R.
cellulose
hydrogels
composites
scaffolds
diffusion
delivery
phema
title_short Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
title_full Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
title_fullStr Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
title_full_unstemmed Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
title_sort Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
dc.creator.none.fl_str_mv Figueiredo, Andrea G. P. R.
Figueiredo, Ana R. P.
Alonso Varona, Ana Isabel
De Matos Fernandes, Susana
Palomares Casado, Teodoro
Rubio Azpeitia, Eva
Barros-Timmons, Ana
Silvestre, Armando J. D.
Neto, Carlos Pascoal
Freire, Carmen S. R.
author Figueiredo, Andrea G. P. R.
author_facet Figueiredo, Andrea G. P. R.
Figueiredo, Ana R. P.
Alonso Varona, Ana Isabel
De Matos Fernandes, Susana
Palomares Casado, Teodoro
Rubio Azpeitia, Eva
Barros-Timmons, Ana
Silvestre, Armando J. D.
Neto, Carlos Pascoal
Freire, Carmen S. R.
author_role author
author2 Figueiredo, Ana R. P.
Alonso Varona, Ana Isabel
De Matos Fernandes, Susana
Palomares Casado, Teodoro
Rubio Azpeitia, Eva
Barros-Timmons, Ana
Silvestre, Armando J. D.
Neto, Carlos Pascoal
Freire, Carmen S. R.
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv cellulose
hydrogels
composites
scaffolds
diffusion
delivery
phema
topic cellulose
hydrogels
composites
scaffolds
diffusion
delivery
phema
description A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.
publishDate 2013
dc.date.none.fl_str_mv 2013
2014
2014
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10810/11289
url http://hdl.handle.net/10810/11289
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://www.hindawi.com/journals/bmri/2013/698141/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:Addi. Archivo Digital para la Docencia y la Investigación
instname:Universidad del País Vasco
instname_str Universidad del País Vasco
reponame_str Addi. Archivo Digital para la Docencia y la Investigación
collection Addi. Archivo Digital para la Docencia y la Investigación
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869424983796613120
score 15.300719

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