Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films

A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical,...

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Detalles Bibliográficos
Autores: Figueiredo, Andrea G. P. R., Figueiredo, Ana R. P., Alonso Varona, Ana Isabel, De Matos Fernandes, Susana, Palomares Casado, Teodoro, Rubio Azpeitia, Eva, Barros-Timmons, Ana, Silvestre, Armando J. D., Neto, Carlos Pascoal, Freire, Carmen S. R.
Tipo de recurso: artículo
Fecha de publicación:2013
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/11289
Acceso en línea:http://hdl.handle.net/10810/11289
Access Level:acceso abierto
Palabra clave:cellulose
hydrogels
composites
scaffolds
diffusion
delivery
phema
Descripción
Sumario:A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.