Role of Ndufs4 in the proliferation of macrophages in galactose media [Dataset]

Parental and Ndufs4−/− RAW 264.7 cells (40,000) were plated on 6-well plates. The cells were cultured in media containing galactose in the complete absence of glucose. The number of viable cells was determined at the indicated time points. Each point represents a biological replicate. Data are shown...

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Detalhes bibliográficos
Autores: Serrano-Lorenzo, Pablo, Gobelli, Dino, Garrido-Moraga, Rocío, Esteban-Amo, María J., López-López, José R., Orduña, Antonio, Fuente, Miguel A. de la, Martín, Miguel Ángel, Simarro-Grande, María
Formato: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/352323
Acesso em linha:http://hdl.handle.net/10261/352323
Access Level:acceso abierto
Palavra-chave:Leigh syndrome patients
Inflammatory cytokine profile
Increasing evidence demonstrate
Div >< p
Mitochondrial respiration alterations
Macrophage effector functions
Effector functions
Maximal respiration
Vitro </
Supernumerary subunit
Shift towards
Phagocytose gram
Ndufs4 </
Mutational hotspot
Modulatory role
Lower levels
Lipopolysaccharide challenge
Improved ability
Critical role
Atp production
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oai_identifier_str oai:digital.csic.es:10261/352323
network_acronym_str ES
network_name_str España
repository_id_str
spelling Role of Ndufs4 in the proliferation of macrophages in galactose media [Dataset]Serrano-Lorenzo, PabloGobelli, DinoGarrido-Moraga, RocíoEsteban-Amo, María J.López-López, José R.Orduña, AntonioFuente, Miguel A. de laMartín, Miguel ÁngelSimarro-Grande, MaríaLeigh syndrome patientsInflammatory cytokine profileIncreasing evidence demonstrateDiv >< pMitochondrial respiration alterationsMacrophage effector functionsEffector functionsMaximal respirationVitro </Supernumerary subunitShift towardsPhagocytose gramNdufs4 </Mutational hotspotModulatory roleLower levelsLipopolysaccharide challengeImproved abilityCritical roleAtp productionParental and Ndufs4−/− RAW 264.7 cells (40,000) were plated on 6-well plates. The cells were cultured in media containing galactose in the complete absence of glucose. The number of viable cells was determined at the indicated time points. Each point represents a biological replicate. Data are shown as the mean ± SD.Peer reviewedFigshareConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202420242023info:eu-repo/semantics/datasethttp://purl.org/coar/resource_type/c_ddb1Publisher's versioninfo:eu-repo/semantics/publishedVersionimage/tiffhttp://hdl.handle.net/10261/352323reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésSerrano-Lorenzo, Pablo; Gobelli, Dino; Garrido-Moraga, Rocío; Esteban-Amo, María J.; López-López, José R.; Orduña, Antonio; Fuente, Miguel A. de la; Martín, Miguel Ángel; Simarro-Grande, María. Development of a novel in vitro model to study the modulatory role of the respiratory complex I in macrophage effector functions. http://dx.doi.org/10.1371/journal.pone.0291442 . http://hdl.handle.net/10261/342166https://doi.org/10.1371/journal.pone.0291442.s008Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3523232026-05-22T06:33:51Z
dc.title.none.fl_str_mv Role of Ndufs4 in the proliferation of macrophages in galactose media [Dataset]
title Role of Ndufs4 in the proliferation of macrophages in galactose media [Dataset]
spellingShingle Role of Ndufs4 in the proliferation of macrophages in galactose media [Dataset]
Serrano-Lorenzo, Pablo
Leigh syndrome patients
Inflammatory cytokine profile
Increasing evidence demonstrate
Div >< p
Mitochondrial respiration alterations
Macrophage effector functions
Effector functions
Maximal respiration
Vitro </
Supernumerary subunit
Shift towards
Phagocytose gram
Ndufs4 </
Mutational hotspot
Modulatory role
Lower levels
Lipopolysaccharide challenge
Improved ability
Critical role
Atp production
title_short Role of Ndufs4 in the proliferation of macrophages in galactose media [Dataset]
title_full Role of Ndufs4 in the proliferation of macrophages in galactose media [Dataset]
title_fullStr Role of Ndufs4 in the proliferation of macrophages in galactose media [Dataset]
title_full_unstemmed Role of Ndufs4 in the proliferation of macrophages in galactose media [Dataset]
title_sort Role of Ndufs4 in the proliferation of macrophages in galactose media [Dataset]
dc.creator.none.fl_str_mv Serrano-Lorenzo, Pablo
Gobelli, Dino
Garrido-Moraga, Rocío
Esteban-Amo, María J.
López-López, José R.
Orduña, Antonio
Fuente, Miguel A. de la
Martín, Miguel Ángel
Simarro-Grande, María
author Serrano-Lorenzo, Pablo
author_facet Serrano-Lorenzo, Pablo
Gobelli, Dino
Garrido-Moraga, Rocío
Esteban-Amo, María J.
López-López, José R.
Orduña, Antonio
Fuente, Miguel A. de la
Martín, Miguel Ángel
Simarro-Grande, María
author_role author
author2 Gobelli, Dino
Garrido-Moraga, Rocío
Esteban-Amo, María J.
López-López, José R.
Orduña, Antonio
Fuente, Miguel A. de la
Martín, Miguel Ángel
Simarro-Grande, María
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Leigh syndrome patients
Inflammatory cytokine profile
Increasing evidence demonstrate
Div >< p
Mitochondrial respiration alterations
Macrophage effector functions
Effector functions
Maximal respiration
Vitro </
Supernumerary subunit
Shift towards
Phagocytose gram
Ndufs4 </
Mutational hotspot
Modulatory role
Lower levels
Lipopolysaccharide challenge
Improved ability
Critical role
Atp production
topic Leigh syndrome patients
Inflammatory cytokine profile
Increasing evidence demonstrate
Div >< p
Mitochondrial respiration alterations
Macrophage effector functions
Effector functions
Maximal respiration
Vitro </
Supernumerary subunit
Shift towards
Phagocytose gram
Ndufs4 </
Mutational hotspot
Modulatory role
Lower levels
Lipopolysaccharide challenge
Improved ability
Critical role
Atp production
description Parental and Ndufs4−/− RAW 264.7 cells (40,000) were plated on 6-well plates. The cells were cultured in media containing galactose in the complete absence of glucose. The number of viable cells was determined at the indicated time points. Each point represents a biological replicate. Data are shown as the mean ± SD.
publishDate 2023
dc.date.none.fl_str_mv 2023
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/dataset
http://purl.org/coar/resource_type/c_ddb1
Publisher's version
info:eu-repo/semantics/publishedVersion
format dataset
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/352323
url http://hdl.handle.net/10261/352323
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Serrano-Lorenzo, Pablo; Gobelli, Dino; Garrido-Moraga, Rocío; Esteban-Amo, María J.; López-López, José R.; Orduña, Antonio; Fuente, Miguel A. de la; Martín, Miguel Ángel; Simarro-Grande, María. Development of a novel in vitro model to study the modulatory role of the respiratory complex I in macrophage effector functions. http://dx.doi.org/10.1371/journal.pone.0291442 . http://hdl.handle.net/10261/342166
https://doi.org/10.1371/journal.pone.0291442.s008
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv image/tiff
dc.publisher.none.fl_str_mv Figshare
publisher.none.fl_str_mv Figshare
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869424857927647232
score 15,811543

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