CI activity in Ndufs4−/− macrophages [Dataset]

The data shown in Fig 2A were reanalyzed and CI activity is shown as CI/CII (left panel) and CI/CIV (right panel). *, P <0.05; **, P <0.01; ***, P<0.005; ****, P<0.001. Each point represents a biological replicate. Data are shown as the mean ± SEM.

Detalles Bibliográficos
Autores: Serrano-Lorenzo, Pablo, Gobelli, Dino, Garrido-Moraga, Rocío, Esteban-Amo, María J., López-López, José R., Orduña, Antonio, Fuente, Miguel A. de la, Martín, Miguel Ángel, Simarro-Grande, María
Tipo de recurso: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/352341
Acceso en línea:http://hdl.handle.net/10261/352341
Access Level:acceso abierto
Palabra clave:Leigh syndrome patients
Inflammatory cytokine profile
Increasing evidence demonstrate
Div >< p
Mitochondrial respiration alterations
Macrophage effector functions
Effector functions
Maximal respiration
Vitro </
Supernumerary subunit
Shift towards
Phagocytose gram
Ndufs4 </
Mutational hotspot
Modulatory role
Lower levels
Lipopolysaccharide challenge
Improved ability
Critical role
Atp production
Descripción
Sumario:The data shown in Fig 2A were reanalyzed and CI activity is shown as CI/CII (left panel) and CI/CIV (right panel). *, P <0.05; **, P <0.01; ***, P<0.005; ****, P<0.001. Each point represents a biological replicate. Data are shown as the mean ± SEM.

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