DataSheet_1_Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress.pdf [Dataset]

[Introduction]: The Unfolded Protein Response, a mechanism triggered by the cell in response to Endoplasmic reticulum stress, is linked to inflammatory responses. Our aim was to identify novel Unfolded Protein Response-mechanisms that might be involved in triggering or perpetuating the inflammatory...

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Detalhes bibliográficos
Autores: Martín-Adrados, Beatriz, Wculek, Stefanie K., Fernández-Bravo, Sergio, Torres-Ruiz, Raúl, Gómez-Sánchez, María José, Hernández-Walias, José Carlos, Moraes Ferreira, Frederico, Corraliza, Ana María, Sancho, David, Esteban, Vanesa, Rodríguez-Perales, Sandra, Cruz-Adalia, Aránzazu, Nakaya, Helder I., Salas, Azucena, Bernardo, David, Campos-Martín, Yolanda, Martínez-Zamorano, Elena, Muñoz-López, Diego, Gómez del Moral, Manuel, Cubero, Francisco Javier, Blumberg, Richard S., Martínez-Naves, Eduardo
Tipo de documento: conjunto de datos
Estado:Versão publicada
Data de publicação:2023
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/360480
Acesso em linha:http://hdl.handle.net/10261/360480
Access Level:Acceso aberto
Palavra-chave:Inflammatory bowel disease
Inflammation
ER stress
HMGCS2
Unfolded protein response (UPR)
Descrição
Resumo:[Introduction]: The Unfolded Protein Response, a mechanism triggered by the cell in response to Endoplasmic reticulum stress, is linked to inflammatory responses. Our aim was to identify novel Unfolded Protein Response-mechanisms that might be involved in triggering or perpetuating the inflammatory response carried out by the Intestinal Epithelial Cells in the context of Inflammatory Bowel Disease.

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