Exploring data distributions in machine learning models with SOMs

Data quality control is fundamental in data-driven analysis with machine learning (ML) models. In the domain of drug research, there is an increasing interest in the prediction of relevant biocompounds physicochemical properties with ML. In order to build predictive models of good quality, it is imp...

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Detalles Bibliográficos
Autores: König, Caroline|||0000-0002-7543-8686, Vellido Alcacena, Alfredo|||0000-0002-9843-1911
Tipo de recurso: capítulo de libro
Fecha de publicación:2024
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/415031
Acceso en línea:https://hdl.handle.net/2117/415031
https://dx.doi.org/10.1007/978-3-031-67159-3_10
Access Level:acceso abierto
Palabra clave:Machine learning
Self-organizing maps
ADME properties
Random forest
Interpretable machine learning
Data quality
Bioinformatics
Aprenentatge automàtic
Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica
Àrees temàtiques de la UPC::Informàtica::Intel·ligència artificial::Aprenentatge automàtic
Descripción
Sumario:Data quality control is fundamental in data-driven analysis with machine learning (ML) models. In the domain of drug research, there is an increasing interest in the prediction of relevant biocompounds physicochemical properties with ML. In order to build predictive models of good quality, it is important to adequately select representative datasets. In this work, we combine ML prediction and Self-Organizing Maps-based exploration to build an interpretable machine learning model and to characterize those data that are most difficult to predict in the validation stage.