Dataset related to article: Aripiprazole cytotoxicity coincides with activation of the unfolded protein response in human hepatic cells

Folder 1. Aripiprazole at Low Micromolar Concentration Induces ER Stress. This folder contains four folders Folder 1a These jpg files show the analysis by immunoblotting for phosphorylated IRE1, total IRE1, total PERK of cell extracts. Folder 1b. These pzt files show the relative quantification of p...

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Detalles Bibliográficos
Autores: Forno, Francesca, Maatuf, Yossi, Boukeileh, Shatha, Dipta, Priya, Mahameed, Mohamed, Darawshi, Odai, Ferreira, Vítor, Rada, Patricia, García Martínez, Irma, Gross, Einav, Priel, Avi, Valverde, Ángela M., Tirosh, Boaz
Tipo de recurso: conjunto de datos
Fecha de publicación:2021
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/245392
Acceso en línea:http://hdl.handle.net/10261/245392
Access Level:acceso abierto
Palabra clave:Aripiprazole
ER stress
Descripción
Sumario:Folder 1. Aripiprazole at Low Micromolar Concentration Induces ER Stress. This folder contains four folders Folder 1a These jpg files show the analysis by immunoblotting for phosphorylated IRE1, total IRE1, total PERK of cell extracts. Folder 1b. These pzt files show the relative quantification of phosphorylated IRE1 after 24 hours of treatment. Statistical significance is indicated by **P < 0.01; ***P < 0.001 Folder 1c. These 2 jpg files represent a time course of an cell extract vs control (4, 8, 12 and 24 h of IRE1 phosphorylation after Ari treatment. Folder 1d. The jpg files represent analysis of the extract cells after a treatment with Olanzapine.