A binding site for the antibiotic GE81112 in the ribosomal mRNA channel

[Data Availability] The raw electron microscopy movies, cryo-EM maps, and resulting atomic models are available at the EMPIAR, EMDB, and Protein Data Bank (PDB). The PDB accession codes are 9H9H, 9H9I, 9H9J, 9H9K, 9H9L, 9H9M, 9H9N, and 9H8G. The EMDB accession codes are 51964, 51965, 51966, 51967, 5...

Full description

Bibliographic Details
Authors: Schedlbauer, Andreas, Han, Xu, Van Bakel, Wouter, Kaminishi, Tatsuya, Ochoa-Lizarralde, Borja, Iturrioz, Idoia, Çapuni, Retina, Parry, Ransford, Zegarra, Ronny, Gil-Carton, David, López-Alonso, Jorge P., Barragan Sanz, Kristina, Brandi, Letizia, Gualerzi, Claudio O., Fucini, Paola, Connell, Sean R.
Format: article
Status:Published version
Publication Date:2025
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:dnet:digitalcsic_::c625cd707c239e062e9869b5bc77a176
Online Access:http://hdl.handle.net/10261/426031
https://api.elsevier.com/content/abstract/scopus_id/105021483788
Access Level:Open access
Keyword:GE81112
IF1
IF2
IF3
Antibiotic
Cryo-EM
Cryo-electron microscopy
Initiation
Ribosome
Description
Summary:[Data Availability] The raw electron microscopy movies, cryo-EM maps, and resulting atomic models are available at the EMPIAR, EMDB, and Protein Data Bank (PDB). The PDB accession codes are 9H9H, 9H9I, 9H9J, 9H9K, 9H9L, 9H9M, 9H9N, and 9H8G. The EMDB accession codes are 51964, 51965, 51966, 51967, 51968, 51969, 51970, and 51936. Raw data for Data sets 1, 2, and 3 are under EMPIAR accession codes 12517, 12458, and 12456. Data are available from the corresponding authors upon reasonable request.