1,3- DIPHOSPHITE LIGANDS WITH FURANOSIDE BACKBONE: A POWERFUL TOOL IN ASYMMETRIC CATALYSIS
Asymmetric catalysis is part of the asymmetric synthesis and makes possible the transformation of a pro-chiral or racemic substrate into a chiral product using catalytic amounts of the compounds which contain the chiral information. The design of new ligands is perhaps the most crucial step to achie...
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| Tipo de recurso: | tesis doctoral |
| Estado: | Versión publicada |
| Fecha de publicación: | 2009 |
| País: | España |
| Institución: | Universitat Rovira i virgili (URV) |
| Repositorio: | Repositori Institucional de la Universitat Rovira i Virgili |
| OAI Identifier: | oai:urv.cat:TDX:878 |
| Acceso en línea: | https://hdl.handle.net/20.500.11797/TDX878 http://hdl.handle.net/10803/9100 |
| Access Level: | acceso abierto |
| Palabra clave: | 547 - Química orgànica 546 - Química inorgànica 542 - Química pràctica de laboratori. Química preparativa i experimental 54 - Química |
| Sumario: | Asymmetric catalysis is part of the asymmetric synthesis and makes possible the transformation of a pro-chiral or racemic substrate into a chiral product using catalytic amounts of the compounds which contain the chiral information. The design of new ligands is perhaps the most crucial step to achieve the highest levels of reactivity and selectivity. Carbohydrates are the most prominent members of the 'chiral pool'.This thesis focus on the development and application in asymmetric catalysis of new 1,3-diphosphite with carbohydrate backbone. These ligands were successful applied in the Rh-asymmetric hydroformylation of monosubstituted, disubstituted internal and 1,1´-disubstituted alkenes.The effect of the structural modification of these 1,3-diphosphite ligands on the catalytic results of the Pd-allylic alkylation of phenyl-allyl compounds was also studied in this thesis. Finally, the 1,3-diphosphites ligands were applied to stabilize metal nanoparticles. These nanocatalysts were tested in the hydrogenation of pro-chiral o- and m-methylanisole. |
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