Which specific causes of death are associated with short term exposure to fine and coarse particles in Southern Europe? Results from the MED-PARTICLES project

We investigated the short-term effects of particles with aerodynamic diameter less than 2.5μm (PM2.5), between 2.5 and 10μm (PM2.5-10) and less than 10μm (PM10) on deaths from diabetes, cardiac and cerebrovascular causes, lower respiratory tract infections (LRTI) and chronic obstructive pulmonary di...

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Autores: Samoli, Evangelia, Stafoggia, Massimo, Rodopoulou, Sophia, Ostro, Bart, Alessandrini, Ester, Basagaña, Xavier, Pérez Díaz, Julio, Faustini, Annunziata, Gandini, Martina, Karanasiou, Angeliki, Kelessis, Apostolos G., Le Tertre, Alain, Linares, Cristina, Ranzi, Andrea, Scarinzi, Cecilia, Katsouyanni, Klea, Forastiere, Francesco
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2014
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/344944
Acceso en línea:http://hdl.handle.net/10261/344944
https://api.elsevier.com/content/abstract/scopus_id/84896528894
Access Level:acceso abierto
Palabra clave:Time series analysis
COPD
Cardiac
Cerebrovascular
Coarse particles
Diabetes
Fine particles
Mortality
Particulate matter
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
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spelling Which specific causes of death are associated with short term exposure to fine and coarse particles in Southern Europe? Results from the MED-PARTICLES projectSamoli, EvangeliaStafoggia, MassimoRodopoulou, SophiaOstro, BartAlessandrini, EsterBasagaña, XavierPérez Díaz, JulioFaustini, AnnunziataGandini, MartinaKaranasiou, AngelikiKelessis, Apostolos G.Le Tertre, AlainLinares, CristinaRanzi, AndreaScarinzi, CeciliaKatsouyanni, KleaForastiere, FrancescoTime series analysisCOPDCardiacCerebrovascularCoarse particlesDiabetesFine particlesMortalityParticulate matterhttp://metadata.un.org/sdg/3Ensure healthy lives and promote well-being for all at all agesWe investigated the short-term effects of particles with aerodynamic diameter less than 2.5μm (PM2.5), between 2.5 and 10μm (PM2.5-10) and less than 10μm (PM10) on deaths from diabetes, cardiac and cerebrovascular causes, lower respiratory tract infections (LRTI) and chronic obstructive pulmonary disease (COPD) in 10 European Mediterranean metropolitan areas participating in the MED-PARTICLES project during 2001-2010. In the first stage of the analysis, data from each city were analyzed separately using Poisson regression models, whereas in the second stage, the city-specific air pollution estimates were combined to obtain overall estimates. We investigated the effects following immediate (lags 0-1), delayed (lags 2-5) and prolonged exposure (lags 0-5) and effect modification patterns by season. We evaluated the sensitivity of our results to co-pollutant exposures or city-specific model choice. We applied threshold models to investigate the pattern of selected associations. For a 10μg/m(3) increase in two days' PM2.5 exposure there was a 1.23% (95% confidence interval (95% CI): -1.63%, 4.17%) increase in diabetes deaths, while six days' exposure statistically significantly increased cardiac deaths by 1.33% (95% CI: 0.27, 2.40%), COPD deaths by 2.53% (95% CI: -0.01%, 5.14%) and LRTI deaths by 1.37% (95% CI: -1.94%, 4.78%). PM2.5 results were robust to co-pollutant adjustments and alternative modeling approaches. Stronger effects were observed in the warm season. Coarse particles displayed positive, even if not statistically significant, associations with mortality due to diabetes and cardiac causes that were more variable depending on exposure period, co-pollutant and seasonality adjustment. Our findings provide support for positive associations between PM2.5 and mortality due to diabetes, cardiac causes, COPD, and to a lesser degree to cerebrovascular causes, in the European Mediterranean region, which seem to drive the particles short-term health effects.The authors declare that they have no actual or potential competing financial interests. Research described in this article was conducted under the Grant Agreement EU LIFE + ENV/IT/327.Peer reviewedElsevierConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202420242014info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/344944https://api.elsevier.com/content/abstract/scopus_id/84896528894reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésEnvironment internationalhttps://doi.org/10.1016/j.envint.2014.02.013Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3449442026-05-22T06:33:51Z
dc.title.none.fl_str_mv Which specific causes of death are associated with short term exposure to fine and coarse particles in Southern Europe? Results from the MED-PARTICLES project
title Which specific causes of death are associated with short term exposure to fine and coarse particles in Southern Europe? Results from the MED-PARTICLES project
spellingShingle Which specific causes of death are associated with short term exposure to fine and coarse particles in Southern Europe? Results from the MED-PARTICLES project
Samoli, Evangelia
Time series analysis
COPD
Cardiac
Cerebrovascular
Coarse particles
Diabetes
Fine particles
Mortality
Particulate matter
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
title_short Which specific causes of death are associated with short term exposure to fine and coarse particles in Southern Europe? Results from the MED-PARTICLES project
title_full Which specific causes of death are associated with short term exposure to fine and coarse particles in Southern Europe? Results from the MED-PARTICLES project
title_fullStr Which specific causes of death are associated with short term exposure to fine and coarse particles in Southern Europe? Results from the MED-PARTICLES project
title_full_unstemmed Which specific causes of death are associated with short term exposure to fine and coarse particles in Southern Europe? Results from the MED-PARTICLES project
title_sort Which specific causes of death are associated with short term exposure to fine and coarse particles in Southern Europe? Results from the MED-PARTICLES project
dc.creator.none.fl_str_mv Samoli, Evangelia
Stafoggia, Massimo
Rodopoulou, Sophia
Ostro, Bart
Alessandrini, Ester
Basagaña, Xavier
Pérez Díaz, Julio
Faustini, Annunziata
Gandini, Martina
Karanasiou, Angeliki
Kelessis, Apostolos G.
Le Tertre, Alain
Linares, Cristina
Ranzi, Andrea
Scarinzi, Cecilia
Katsouyanni, Klea
Forastiere, Francesco
author Samoli, Evangelia
author_facet Samoli, Evangelia
Stafoggia, Massimo
Rodopoulou, Sophia
Ostro, Bart
Alessandrini, Ester
Basagaña, Xavier
Pérez Díaz, Julio
Faustini, Annunziata
Gandini, Martina
Karanasiou, Angeliki
Kelessis, Apostolos G.
Le Tertre, Alain
Linares, Cristina
Ranzi, Andrea
Scarinzi, Cecilia
Katsouyanni, Klea
Forastiere, Francesco
author_role author
author2 Stafoggia, Massimo
Rodopoulou, Sophia
Ostro, Bart
Alessandrini, Ester
Basagaña, Xavier
Pérez Díaz, Julio
Faustini, Annunziata
Gandini, Martina
Karanasiou, Angeliki
Kelessis, Apostolos G.
Le Tertre, Alain
Linares, Cristina
Ranzi, Andrea
Scarinzi, Cecilia
Katsouyanni, Klea
Forastiere, Francesco
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Time series analysis
COPD
Cardiac
Cerebrovascular
Coarse particles
Diabetes
Fine particles
Mortality
Particulate matter
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
topic Time series analysis
COPD
Cardiac
Cerebrovascular
Coarse particles
Diabetes
Fine particles
Mortality
Particulate matter
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
description We investigated the short-term effects of particles with aerodynamic diameter less than 2.5μm (PM2.5), between 2.5 and 10μm (PM2.5-10) and less than 10μm (PM10) on deaths from diabetes, cardiac and cerebrovascular causes, lower respiratory tract infections (LRTI) and chronic obstructive pulmonary disease (COPD) in 10 European Mediterranean metropolitan areas participating in the MED-PARTICLES project during 2001-2010. In the first stage of the analysis, data from each city were analyzed separately using Poisson regression models, whereas in the second stage, the city-specific air pollution estimates were combined to obtain overall estimates. We investigated the effects following immediate (lags 0-1), delayed (lags 2-5) and prolonged exposure (lags 0-5) and effect modification patterns by season. We evaluated the sensitivity of our results to co-pollutant exposures or city-specific model choice. We applied threshold models to investigate the pattern of selected associations. For a 10μg/m(3) increase in two days' PM2.5 exposure there was a 1.23% (95% confidence interval (95% CI): -1.63%, 4.17%) increase in diabetes deaths, while six days' exposure statistically significantly increased cardiac deaths by 1.33% (95% CI: 0.27, 2.40%), COPD deaths by 2.53% (95% CI: -0.01%, 5.14%) and LRTI deaths by 1.37% (95% CI: -1.94%, 4.78%). PM2.5 results were robust to co-pollutant adjustments and alternative modeling approaches. Stronger effects were observed in the warm season. Coarse particles displayed positive, even if not statistically significant, associations with mortality due to diabetes and cardiac causes that were more variable depending on exposure period, co-pollutant and seasonality adjustment. Our findings provide support for positive associations between PM2.5 and mortality due to diabetes, cardiac causes, COPD, and to a lesser degree to cerebrovascular causes, in the European Mediterranean region, which seem to drive the particles short-term health effects.
publishDate 2014
dc.date.none.fl_str_mv 2014
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/344944
https://api.elsevier.com/content/abstract/scopus_id/84896528894
url http://hdl.handle.net/10261/344944
https://api.elsevier.com/content/abstract/scopus_id/84896528894
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Environment international
https://doi.org/10.1016/j.envint.2014.02.013
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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