Associations between fine and coarse particles and mortality in Mediterranean cities: results from the MED-PARTICLES project

Few studies have investigated the independent health effects of different size fractions of particulate matter (PM) in multiple locations, especially in Europe. We estimated the short-term effects of PM with aerodynamic diameter = 10 µm (PM10), = 2.5 µm (PM2.5), and between 2.5 and 10 µm (PM2.5–10)...

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Detalles Bibliográficos
Autores: Samoli, Evangelia, Stafoggia, Massimo, Rodopoulou, Sophia, Ostro, Bart, Declercq, Christophe, Alessandrini, Ester, Díaz, Julio, Karanasiou, Angeliki, Kelessis, Apostolos G., Le Tertre, Alain, Pandolfi, Paolo, Randi, Giorgia, Scarinzi, Cecilia, Zauli-Sajani, Stefano, Katsouyanni, Klea, Forastiere, Francesco, Study Group, MED-PARTICLES, Agis Cherta, David|||0000-0002-7283-6902
Tipo de recurso: artículo
Fecha de publicación:2013
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/175969
Acceso en línea:https://hdl.handle.net/2117/175969
https://dx.doi.org/10.1289/ehp.1206124
Access Level:acceso abierto
Palabra clave:Air -- Pollution
Cardiovascular system -- Diseases
Coarse particles
Fine particles
Mediterranean
Mortality
Particulate matter
Time series
Aire -- Contaminació
Sistema cardiovascular -- Malalties
Àrees temàtiques de la UPC::Ciències de la salut::Impacte ambiental
Descripción
Sumario:Few studies have investigated the independent health effects of different size fractions of particulate matter (PM) in multiple locations, especially in Europe. We estimated the short-term effects of PM with aerodynamic diameter = 10 µm (PM10), = 2.5 µm (PM2.5), and between 2.5 and 10 µm (PM2.5–10) on all-cause, cardiovascular, and respiratory mortality in 10 European Mediterranean metropolitan areas within the MEDPARTICLES project. We analyzed data from each city using Poisson regression models, and combined cityspecific estimates to derive overall effect estimates. We evaluated the sensitivity of our estimates to co-pollutant exposures and city-specific model choice, and investigated effect modification by age, sex, and season. We applied distributed lag and threshold models to investigate temporal patterns of associations. A 10-µg/m3 increase in PM2.5 was associated with a 0.55% (95% CI: 0.27, 0.84%) increase in all-cause mortality (0–1 day cumulative lag), and a 1.91% increase (95% CI: 0.71, 3.12%) in respiratory mortality (0–5 day lag). In general, associations were stronger for cardiovascular and respiratory mortality than all-cause mortality, during warm versus cold months, and among those = 75 versus < 75 years of age. Associations with PM2.5–10 were positive but not statistically significant in most analyses, whereas associations with PM10 seemed to be driven by PM2.5. We found evidence of adverse effects of PM2.5 on mortality outcomes in the European Mediterranean region. Associations with PM2.5–10 were positive but smaller in magnitude. Associations were stronger for respiratory mortality when cumulative exposures were lagged over 0–5 days, and were modified by season and age.

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