Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model

The chemical composition and the surface characteristics of dental implants are factors that have a decisive effect on the osseointegration process. The surface characterization at the compositional and topographic level of three dental implants available in the market was performed with different s...

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Autores: Rizo-Gorrita, María, Fernández Asián, Ignacio Rafael, Garcia-de-Frenza, Andreina, Vazquez-Pachon, Celia, Serrera Figallo, María de los Ángeles, Torres-Lagares, Daniel, Gutiérrez Pérez, José Luis
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Recursos:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/101987
Acesso em linha:https://hdl.handle.net/11441/101987
https://doi.org/10.3390/app10144790
Access Level:acceso abierto
Palavra-chave:Dental implant surfaces
Surface roughness
Titanium
Osseointegration
Bone–implant interface
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spelling Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit ModelRizo-Gorrita, MaríaFernández Asián, Ignacio RafaelGarcia-de-Frenza, AndreinaVazquez-Pachon, CeliaSerrera Figallo, María de los ÁngelesTorres-Lagares, DanielGutiérrez Pérez, José LuisDental implant surfacesSurface roughnessTitaniumOsseointegrationBone–implant interfaceThe chemical composition and the surface characteristics of dental implants are factors that have a decisive effect on the osseointegration process. The surface characterization at the compositional and topographic level of three dental implants available in the market was performed with different surface treatments: (1) sandblasted and acid etched surface (SLA), (2) hydroxyapatite (HA) and tricalcium phosphate (TCP) blasted surface (HA/TCP), and (3) HA-blasted and non-etching acid washed surface (HA + AW). In addition, an in vitro viability study of MG-63 osteoblast cells was performed with a JC-1 test. To complete the study, an in vivo study was conducted in New Zealand rabbits. The study analyzed the histometric characteristics of the bone formed around the implants at the level of area, volume, bone density, accumulated bone density, and bone–implant contact (BIC). The rabbits were sacrificed at 6 weeks after implants were placed in the tibial metaphysis. No statistically significant differences were observed at the level of cell viability or histometric parameters between the different study groups (p > 0.05). SLA and HA/TCP surfaces were the ones that obtained a higher BIC value. Taking into account the limitations of this study, it can be concluded that the different implant surfaces analyzed favor a good bone response.2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/101987https://doi.org/10.3390/app10144790reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)Inglésinfo:eu-repo/semantics/openAccessoai:idus.us.es:11441/1019872026-06-17T12:51:07Z
dc.title.none.fl_str_mv Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model
title Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model
spellingShingle Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model
Rizo-Gorrita, María
Dental implant surfaces
Surface roughness
Titanium
Osseointegration
Bone–implant interface
title_short Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model
title_full Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model
title_fullStr Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model
title_full_unstemmed Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model
title_sort Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model
dc.creator.none.fl_str_mv Rizo-Gorrita, María
Fernández Asián, Ignacio Rafael
Garcia-de-Frenza, Andreina
Vazquez-Pachon, Celia
Serrera Figallo, María de los Ángeles
Torres-Lagares, Daniel
Gutiérrez Pérez, José Luis
author Rizo-Gorrita, María
author_facet Rizo-Gorrita, María
Fernández Asián, Ignacio Rafael
Garcia-de-Frenza, Andreina
Vazquez-Pachon, Celia
Serrera Figallo, María de los Ángeles
Torres-Lagares, Daniel
Gutiérrez Pérez, José Luis
author_role author
author2 Fernández Asián, Ignacio Rafael
Garcia-de-Frenza, Andreina
Vazquez-Pachon, Celia
Serrera Figallo, María de los Ángeles
Torres-Lagares, Daniel
Gutiérrez Pérez, José Luis
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Dental implant surfaces
Surface roughness
Titanium
Osseointegration
Bone–implant interface
topic Dental implant surfaces
Surface roughness
Titanium
Osseointegration
Bone–implant interface
description The chemical composition and the surface characteristics of dental implants are factors that have a decisive effect on the osseointegration process. The surface characterization at the compositional and topographic level of three dental implants available in the market was performed with different surface treatments: (1) sandblasted and acid etched surface (SLA), (2) hydroxyapatite (HA) and tricalcium phosphate (TCP) blasted surface (HA/TCP), and (3) HA-blasted and non-etching acid washed surface (HA + AW). In addition, an in vitro viability study of MG-63 osteoblast cells was performed with a JC-1 test. To complete the study, an in vivo study was conducted in New Zealand rabbits. The study analyzed the histometric characteristics of the bone formed around the implants at the level of area, volume, bone density, accumulated bone density, and bone–implant contact (BIC). The rabbits were sacrificed at 6 weeks after implants were placed in the tibial metaphysis. No statistically significant differences were observed at the level of cell viability or histometric parameters between the different study groups (p > 0.05). SLA and HA/TCP surfaces were the ones that obtained a higher BIC value. Taking into account the limitations of this study, it can be concluded that the different implant surfaces analyzed favor a good bone response.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/101987
https://doi.org/10.3390/app10144790
url https://hdl.handle.net/11441/101987
https://doi.org/10.3390/app10144790
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
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