Pediatric Community-Acquired Bone and Joint Staphylococcus Aureus Infections In Europe Severe Infections are Associated to Panton-Valentine Leucocidin Presence

To analyze host and pathogen factors related to disease severity of community-acquired bone and joint infections in children, a cohort of pediatric patients was prospectively recruited from 13 centers in 7 European countries. A total of 85 children were included, 11 (13%) had a severe infection. Pan...

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Autores: Gijón M, Bellusci M, Petraitiene B, Noguera-Julian A, Glikman D, Saavedra-Lozano J, Neth O, Daskalaki M, Zilinskaite V, Kaiser-Labusch P, Prieto L, Rojo P
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p17538
Acceso en línea:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=17538
Access Level:acceso abierto
Palabra clave:aureus
children
osteomyelitis
arthritis
PVL
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spelling Pediatric Community-Acquired Bone and Joint Staphylococcus Aureus Infections In Europe Severe Infections are Associated to Panton-Valentine Leucocidin PresenceGijón MBellusci MPetraitiene BNoguera-Julian AGlikman DSaavedra-Lozano JNeth ODaskalaki MZilinskaite VKaiser-Labusch PPrieto LRojo PaureuschildrenosteomyelitisarthritisPVLTo analyze host and pathogen factors related to disease severity of community-acquired bone and joint infections in children, a cohort of pediatric patients was prospectively recruited from 13 centers in 7 European countries. A total of 85 children were included, 11 (13%) had a severe infection. Panton-Valentine leukocidin-positive isolates were 17%, and 6% of the isolates were methicillin-resistant Staphylococcus aureus. Multivariate analysis identified Panton-Valentine leukocidin presence (adjusted odds ratio, 12.6; P = 0.01) as the only factor independently associated with severe outcome, regardless of methicillin resistance.LIPPINCOTT WILLIAMS & WILKINS2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=17538PEDIATRIC INFECTIOUS DISEASE JOURNALISSN: 08913668ISSNe: 15320987reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p175382026-05-27T12:37:41Z
dc.title.none.fl_str_mv Pediatric Community-Acquired Bone and Joint Staphylococcus Aureus Infections In Europe Severe Infections are Associated to Panton-Valentine Leucocidin Presence
title Pediatric Community-Acquired Bone and Joint Staphylococcus Aureus Infections In Europe Severe Infections are Associated to Panton-Valentine Leucocidin Presence
spellingShingle Pediatric Community-Acquired Bone and Joint Staphylococcus Aureus Infections In Europe Severe Infections are Associated to Panton-Valentine Leucocidin Presence
Gijón M
aureus
children
osteomyelitis
arthritis
PVL
title_short Pediatric Community-Acquired Bone and Joint Staphylococcus Aureus Infections In Europe Severe Infections are Associated to Panton-Valentine Leucocidin Presence
title_full Pediatric Community-Acquired Bone and Joint Staphylococcus Aureus Infections In Europe Severe Infections are Associated to Panton-Valentine Leucocidin Presence
title_fullStr Pediatric Community-Acquired Bone and Joint Staphylococcus Aureus Infections In Europe Severe Infections are Associated to Panton-Valentine Leucocidin Presence
title_full_unstemmed Pediatric Community-Acquired Bone and Joint Staphylococcus Aureus Infections In Europe Severe Infections are Associated to Panton-Valentine Leucocidin Presence
title_sort Pediatric Community-Acquired Bone and Joint Staphylococcus Aureus Infections In Europe Severe Infections are Associated to Panton-Valentine Leucocidin Presence
dc.creator.none.fl_str_mv Gijón M
Bellusci M
Petraitiene B
Noguera-Julian A
Glikman D
Saavedra-Lozano J
Neth O
Daskalaki M
Zilinskaite V
Kaiser-Labusch P
Prieto L
Rojo P
author Gijón M
author_facet Gijón M
Bellusci M
Petraitiene B
Noguera-Julian A
Glikman D
Saavedra-Lozano J
Neth O
Daskalaki M
Zilinskaite V
Kaiser-Labusch P
Prieto L
Rojo P
author_role author
author2 Bellusci M
Petraitiene B
Noguera-Julian A
Glikman D
Saavedra-Lozano J
Neth O
Daskalaki M
Zilinskaite V
Kaiser-Labusch P
Prieto L
Rojo P
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv aureus
children
osteomyelitis
arthritis
PVL
topic aureus
children
osteomyelitis
arthritis
PVL
description To analyze host and pathogen factors related to disease severity of community-acquired bone and joint infections in children, a cohort of pediatric patients was prospectively recruited from 13 centers in 7 European countries. A total of 85 children were included, 11 (13%) had a severe infection. Panton-Valentine leukocidin-positive isolates were 17%, and 6% of the isolates were methicillin-resistant Staphylococcus aureus. Multivariate analysis identified Panton-Valentine leukocidin presence (adjusted odds ratio, 12.6; P = 0.01) as the only factor independently associated with severe outcome, regardless of methicillin resistance.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=17538
url https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=17538
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv LIPPINCOTT WILLIAMS & WILKINS
publisher.none.fl_str_mv LIPPINCOTT WILLIAMS & WILKINS
dc.source.none.fl_str_mv PEDIATRIC INFECTIOUS DISEASE JOURNAL
ISSN: 08913668
ISSNe: 15320987
reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname:Fundació Sant Joan de Déu
instname_str Fundació Sant Joan de Déu
reponame_str r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
collection r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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