First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia

Optimal antituberculosis therapy is essential for favorable clinical outcomes. Peak plasma concentrations of first-line antituberculosis drugs in infants with living HIV receiving WHO-recommended dosing were low compared with reference values for adults, supporting studies on increased doses of firs...

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Autores: Chabala, Chishala, Jacobs, Tom G., Moraleda, Cinta, Ndaferankhande, John M., Mumbiro, Vivian, Passanduca, Alfeu, Namuziya, Natasha, Tagarro García, Alfredo, Aarnoutse, Rob E., EMPIRICAL Clinical Trial Group, Et al.
Formato: artículo
Fecha de publicación:2023
País:España
Recursos:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/12395
Acesso em linha:http://hdl.handle.net/11268/12395
Access Level:acceso abierto
Palavra-chave:Síndrome de inmunodeficiencia adquirida
Síndrome respiratorio agudo grave
Antituberculosos
Aparato respiratorio
Enfermedad transmisible
Pediatría
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spelling First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe PneumoniaChabala, ChishalaJacobs, Tom G.Moraleda, CintaNdaferankhande, John M.Mumbiro, VivianPassanduca, AlfeuNamuziya, NatashaTagarro García, AlfredoAarnoutse, Rob E.EMPIRICAL Clinical Trial GroupEt al.Síndrome de inmunodeficiencia adquiridaSíndrome respiratorio agudo graveAntituberculososAparato respiratorioEnfermedad transmisiblePediatríaOptimal antituberculosis therapy is essential for favorable clinical outcomes. Peak plasma concentrations of first-line antituberculosis drugs in infants with living HIV receiving WHO-recommended dosing were low compared with reference values for adults, supporting studies on increased doses of first-line TB drugs in infants.20232023-11-2720232023-01-0120232023-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/11268/12395reponame:ABACUS. Repositorio de Producción Científicainstname:Universidad Europea (UEM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:abacus.universidadeuropea.com:11268/123952026-06-11T12:41:27Z
dc.title.none.fl_str_mv First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia
title First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia
spellingShingle First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia
Chabala, Chishala
Síndrome de inmunodeficiencia adquirida
Síndrome respiratorio agudo grave
Antituberculosos
Aparato respiratorio
Enfermedad transmisible
Pediatría
title_short First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia
title_full First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia
title_fullStr First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia
title_full_unstemmed First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia
title_sort First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia
dc.creator.none.fl_str_mv Chabala, Chishala
Jacobs, Tom G.
Moraleda, Cinta
Ndaferankhande, John M.
Mumbiro, Vivian
Passanduca, Alfeu
Namuziya, Natasha
Tagarro García, Alfredo
Aarnoutse, Rob E.
EMPIRICAL Clinical Trial Group
Et al.
author Chabala, Chishala
author_facet Chabala, Chishala
Jacobs, Tom G.
Moraleda, Cinta
Ndaferankhande, John M.
Mumbiro, Vivian
Passanduca, Alfeu
Namuziya, Natasha
Tagarro García, Alfredo
Aarnoutse, Rob E.
EMPIRICAL Clinical Trial Group
Et al.
author_role author
author2 Jacobs, Tom G.
Moraleda, Cinta
Ndaferankhande, John M.
Mumbiro, Vivian
Passanduca, Alfeu
Namuziya, Natasha
Tagarro García, Alfredo
Aarnoutse, Rob E.
EMPIRICAL Clinical Trial Group
Et al.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Síndrome de inmunodeficiencia adquirida
Síndrome respiratorio agudo grave
Antituberculosos
Aparato respiratorio
Enfermedad transmisible
Pediatría
topic Síndrome de inmunodeficiencia adquirida
Síndrome respiratorio agudo grave
Antituberculosos
Aparato respiratorio
Enfermedad transmisible
Pediatría
description Optimal antituberculosis therapy is essential for favorable clinical outcomes. Peak plasma concentrations of first-line antituberculosis drugs in infants with living HIV receiving WHO-recommended dosing were low compared with reference values for adults, supporting studies on increased doses of first-line TB drugs in infants.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-11-27
2023
2023-01-01
2023
2023-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/11268/12395
url http://hdl.handle.net/11268/12395
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:ABACUS. Repositorio de Producción Científica
instname:Universidad Europea (UEM)
instname_str Universidad Europea (UEM)
reponame_str ABACUS. Repositorio de Producción Científica
collection ABACUS. Repositorio de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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