First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia

Optimal antituberculosis therapy is essential for favorable clinical outcomes. Peak plasma concentrations of first-line antituberculosis drugs in infants with living HIV receiving WHO-recommended dosing were low compared with reference values for adults, supporting studies on increased doses of firs...

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Detalles Bibliográficos
Autores: Chabala, Chishala, Jacobs, Tom G., Moraleda, Cinta, Ndaferankhande, John M., Mumbiro, Vivian, Passanduca, Alfeu, Namuziya, Natasha, Tagarro García, Alfredo, Aarnoutse, Rob E., EMPIRICAL Clinical Trial Group, Et al.
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/12395
Acceso en línea:http://hdl.handle.net/11268/12395
Access Level:acceso abierto
Palabra clave:Síndrome de inmunodeficiencia adquirida
Síndrome respiratorio agudo grave
Antituberculosos
Aparato respiratorio
Enfermedad transmisible
Pediatría
Descripción
Sumario:Optimal antituberculosis therapy is essential for favorable clinical outcomes. Peak plasma concentrations of first-line antituberculosis drugs in infants with living HIV receiving WHO-recommended dosing were low compared with reference values for adults, supporting studies on increased doses of first-line TB drugs in infants.

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