On the road to biological blood diagnosis of Alzheimer's disease? Vers un diagnostic biologique sanguin de la maladie d Alzheimer ?

The growing number of people suffering from Alzheimer s disease (AD) represents a major public health problem. The diagnosis of AD is multidisciplinary and involves the use of amyloid and tau biomarkers measured in cerebrospinal fluid. Recent advances in analytical techniques now allow us to measure...

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Detalles Bibliográficos
Autores: Delaby, Constance|||0000-0002-8606-6814, Lehmann, Sylvain|||0000-0001-6117-562X
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:francés
OAI Identifier:oai:ddd.uab.cat:306341
Acceso en línea:https://ddd.uab.cat/record/306341
https://dx.doi.org/urn:doi:10.1051/medsci/2024037
Access Level:acceso abierto
Palabra clave:Alzheimer Disease
Amyloid beta-Peptides
Biomarkers
Diagnosis, Differential
Humans
Tau Proteins
Descripción
Sumario:The growing number of people suffering from Alzheimer s disease (AD) represents a major public health problem. The diagnosis of AD is multidisciplinary and involves the use of amyloid and tau biomarkers measured in cerebrospinal fluid. Recent advances in analytical techniques now allow us to measure these biomarkers in blood. Blood biomarkers offer particularly promising potential for early, minimally invasive detection of AD, as well as for differential diagnosis of dementia and patient follow-up. The aim of this review is to provide an overview of current and candidate blood biomarkers for AD, their informative value, and their potential to be integrated into clinical practice in the near future.