Revisión crítica de la estimulación subtalámica en la enfermedad de Parkinson

The authors critically review subthalamic nucleus (STN) stimulation for Parkinson's disease (PD) at long follow-up (3-5 years). Subthalamic stimulation induce a significant improvement during the "off" medication in the assessment motor score UPDRS (Unified Parkinson Disease Rating Sc...

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Autores: Guridi-Legarra, J. (Jorge)|||/items/fe564c83-4ecb-4600-b7e6-ca5a8dd7e2ee, Rodriguez-Oroz, M.C. (María Cruz)|||/items/ba71432e-1a59-4a6d-87af-ba74627ba030, Clavero, P. (P.)|||/items/316f1018-c5a9-41b8-929c-96bedb8131bd, Manrique, M. (Miguel)|||/items/ec6d7294-2abf-48e9-b988-019b4a49a6ba
Tipo de recurso: artículo
Fecha de publicación:2009
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:español
OAI Identifier:oai:dadun.unav.edu:10171/22541
Acceso en línea:https://hdl.handle.net/10171/22541
Access Level:acceso abierto
Palabra clave:Parkinson´s disease
Deep brain stimulation
Pallidal stimulation
Neurocirugía
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spelling Revisión crítica de la estimulación subtalámica en la enfermedad de ParkinsonCritical review of the subthalamic stimulation in Parkinson´s diseaseGuridi-Legarra, J. (Jorge)|||/items/fe564c83-4ecb-4600-b7e6-ca5a8dd7e2eeRodriguez-Oroz, M.C. (María Cruz)|||/items/ba71432e-1a59-4a6d-87af-ba74627ba030Clavero, P. (P.)|||/items/316f1018-c5a9-41b8-929c-96bedb8131bdManrique, M. (Miguel)|||/items/ec6d7294-2abf-48e9-b988-019b4a49a6baParkinson´s diseaseDeep brain stimulationPallidal stimulationNeurocirugíaThe authors critically review subthalamic nucleus (STN) stimulation for Parkinson's disease (PD) at long follow-up (3-5 years). Subthalamic stimulation induce a significant improvement during the "off" medication in the assessment motor score UPDRS (Unified Parkinson Disease Rating Scale) 3-5 years after surgery. Results show that the benefits obtained in tremor, rigidity, bradykinesia, dyskinesias induced by medication and levodopa reduction are significantly maintained during long term. The improvement in other clinical signs as gait and postural stability at long follow-up are not maintained comparing with the benefits obtained one year after surgery. A high percentage of patients show a cognitive disturbance during the follow-up period that may be correlated with the disease progression. The conclusion is that bilateral STN stimulation is an effective treatment for PD patients at long term but it should be considered earlier in the course of PDSociedad Española de NeurocirugíaDadun. Depósito Académico Digital Universidad de Navarra20122012-06-1220092009-01-0120092009-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/22541reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraEspañolspaopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/225412026-06-21T12:47:57Z
dc.title.none.fl_str_mv Revisión crítica de la estimulación subtalámica en la enfermedad de Parkinson
Critical review of the subthalamic stimulation in Parkinson´s disease
title Revisión crítica de la estimulación subtalámica en la enfermedad de Parkinson
spellingShingle Revisión crítica de la estimulación subtalámica en la enfermedad de Parkinson
Guridi-Legarra, J. (Jorge)|||/items/fe564c83-4ecb-4600-b7e6-ca5a8dd7e2ee
Parkinson´s disease
Deep brain stimulation
Pallidal stimulation
Neurocirugía
title_short Revisión crítica de la estimulación subtalámica en la enfermedad de Parkinson
title_full Revisión crítica de la estimulación subtalámica en la enfermedad de Parkinson
title_fullStr Revisión crítica de la estimulación subtalámica en la enfermedad de Parkinson
title_full_unstemmed Revisión crítica de la estimulación subtalámica en la enfermedad de Parkinson
title_sort Revisión crítica de la estimulación subtalámica en la enfermedad de Parkinson
dc.creator.none.fl_str_mv Guridi-Legarra, J. (Jorge)|||/items/fe564c83-4ecb-4600-b7e6-ca5a8dd7e2ee
Rodriguez-Oroz, M.C. (María Cruz)|||/items/ba71432e-1a59-4a6d-87af-ba74627ba030
Clavero, P. (P.)|||/items/316f1018-c5a9-41b8-929c-96bedb8131bd
Manrique, M. (Miguel)|||/items/ec6d7294-2abf-48e9-b988-019b4a49a6ba
author Guridi-Legarra, J. (Jorge)|||/items/fe564c83-4ecb-4600-b7e6-ca5a8dd7e2ee
author_facet Guridi-Legarra, J. (Jorge)|||/items/fe564c83-4ecb-4600-b7e6-ca5a8dd7e2ee
Rodriguez-Oroz, M.C. (María Cruz)|||/items/ba71432e-1a59-4a6d-87af-ba74627ba030
Clavero, P. (P.)|||/items/316f1018-c5a9-41b8-929c-96bedb8131bd
Manrique, M. (Miguel)|||/items/ec6d7294-2abf-48e9-b988-019b4a49a6ba
author_role author
author2 Rodriguez-Oroz, M.C. (María Cruz)|||/items/ba71432e-1a59-4a6d-87af-ba74627ba030
Clavero, P. (P.)|||/items/316f1018-c5a9-41b8-929c-96bedb8131bd
Manrique, M. (Miguel)|||/items/ec6d7294-2abf-48e9-b988-019b4a49a6ba
author2_role author
author
author
dc.contributor.none.fl_str_mv Dadun. Depósito Académico Digital Universidad de Navarra
dc.subject.none.fl_str_mv Parkinson´s disease
Deep brain stimulation
Pallidal stimulation
Neurocirugía
topic Parkinson´s disease
Deep brain stimulation
Pallidal stimulation
Neurocirugía
description The authors critically review subthalamic nucleus (STN) stimulation for Parkinson's disease (PD) at long follow-up (3-5 years). Subthalamic stimulation induce a significant improvement during the "off" medication in the assessment motor score UPDRS (Unified Parkinson Disease Rating Scale) 3-5 years after surgery. Results show that the benefits obtained in tremor, rigidity, bradykinesia, dyskinesias induced by medication and levodopa reduction are significantly maintained during long term. The improvement in other clinical signs as gait and postural stability at long follow-up are not maintained comparing with the benefits obtained one year after surgery. A high percentage of patients show a cognitive disturbance during the follow-up period that may be correlated with the disease progression. The conclusion is that bilateral STN stimulation is an effective treatment for PD patients at long term but it should be considered earlier in the course of PD
publishDate 2009
dc.date.none.fl_str_mv 2009
2009-01-01
2009
2009-01-01
2012
2012-06-12
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10171/22541
url https://hdl.handle.net/10171/22541
dc.language.none.fl_str_mv Español
spa
language_invalid_str_mv Español
language spa
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedad Española de Neurocirugía
publisher.none.fl_str_mv Sociedad Española de Neurocirugía
dc.source.none.fl_str_mv reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra
instname:Universidad de Navarra
instname_str Universidad de Navarra
reponame_str Dadun. Depósito Académico Digital de la Universidad de Navarra
collection Dadun. Depósito Académico Digital de la Universidad de Navarra
repository.name.fl_str_mv
repository.mail.fl_str_mv
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