Nanoscale thermometry for hyperthermia applications

The importance of high-resolution intracellular thermal sensing and imaging in the field of modern biomedicine has boosted the development of novel nanosized fluorescent systems (fluorescent nanothermometers) as the next generation of probes for intracellular thermal sensing and imaging. This therma...

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Detalles Bibliográficos
Autores: Piñol, Rafael, Brites, Carlos, Silva, Nuno Joâo O., Carlos, Luis D., Millán, Ángel
Tipo de recurso: otro
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/183945
Acceso en línea:http://hdl.handle.net/10261/183945
Access Level:acceso abierto
Palabra clave:Intracellular heating
Nanothermometry
Luminescent thermometry
Magnetic hyperthermia
Optical hyperthermia
Descripción
Sumario:The importance of high-resolution intracellular thermal sensing and imaging in the field of modern biomedicine has boosted the development of novel nanosized fluorescent systems (fluorescent nanothermometers) as the next generation of probes for intracellular thermal sensing and imaging. This thermal mapping requires fluorescent nanothermometers with good biocompatibility and high thermal sensitivity in order to obtain submicrometric and subdegree spatial and thermal resolutions, respectively. This chapter revises the different nanometric systems that have been proposed to date for intracellular thermal sensing and imaging. We also include the later advances in molecular systems based on fluorescent proteins for thermal mapping. A critical overview of the state of the art and the future perspective is also included.