Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study

Background. Although Streptococcus anginosus group (SAG) endocarditis is considered a severe disease associated with abscess formation and embolic events, there is limited evidence to support this assumption. Methods. We performed a retrospective analysis of prospectively collected data from consecu...

Descripción completa

Detalles Bibliográficos
Autores: Escrihuela-Vidal, Francesc, López-Cortés, Luis Eduardo, Escolà-Vergé, Laura, Alarcón González, Arístides de, Cuervo, Guillermo, Sánchez-Porto, Antonio, Fernández-Hidalgo, Nuria, Luque, Rafael, Montejo, Miguel, Miró, José María, Goenaga, Miguel Ángel, Muñoz, Patricia, Valerio, Maricela, Ripa, Marco, Sousa-Regueiro, Dolores, Gurguí, Mercé, Fariñas Álvarez, María del Carmen, Mateu, Lourdes, García Vázquez, Elisa, Gálvez-Acebal, Juan
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad de Cantabria (UC)
Repositorio:UCrea Repositorio Abierto de la Universidad de Cantabria
Idioma:inglés
OAI Identifier:oai:repositorio.unican.es:10902/24994
Acceso en línea:http://hdl.handle.net/10902/24994
Access Level:acceso abierto
Palabra clave:Infective endocarditis
Streptococcus anginosus
Viridans group streptococci
Streptococcus gallolyticus
id ES_ec20fb07b04f0f4e9f42ef4b4ad5454f
oai_identifier_str oai:repositorio.unican.es:10902/24994
network_acronym_str ES
network_name_str España
repository_id_str
spelling Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort StudyEscrihuela-Vidal, FrancescLópez-Cortés, Luis EduardoEscolà-Vergé, LauraAlarcón González, Arístides deCuervo, GuillermoSánchez-Porto, AntonioFernández-Hidalgo, NuriaLuque, RafaelMontejo, MiguelMiró, José MaríaGoenaga, Miguel ÁngelMuñoz, PatriciaValerio, MaricelaRipa, MarcoSousa-Regueiro, DoloresGurguí, MercéFariñas Álvarez, María del CarmenMateu, LourdesGarcía Vázquez, ElisaGálvez-Acebal, JuanInfective endocarditisStreptococcus anginosusViridans group streptococciStreptococcus gallolyticusBackground. Although Streptococcus anginosus group (SAG) endocarditis is considered a severe disease associated with abscess formation and embolic events, there is limited evidence to support this assumption. Methods. We performed a retrospective analysis of prospectively collected data from consecutive patients with definite SAG endocarditis in 28 centers in Spain and Italy. A comparison between cases due to SAG endocarditis and viridans group streptococci (VGS) or Streptococcus gallolyticus group (SGG) was performed in a 1:2 matched analysis. Results. Of 5336 consecutive cases of definite endocarditis, 72 (1.4%) were due to SAG and matched with 144 cases due to VGS/ SGG. SAG endocarditis was community acquired in 64 (88.9%) cases and affected aortic native valve in 29 (40.3%). When com paring SAG and VGS/SGG endocarditis, no significant differences were found in septic shock (8.3% vs 3.5%, P = .116); valve disorder, including perforation (22.2% vs 18.1%, P = .584), pseudoaneurysm (16.7% vs 8.3%, P = .108), or prosthesis dehiscence (1.4% vs 6.3%, P = .170); paravalvular complications, including abscess (25% vs 18.8%, P = .264) and intracardiac fistula (5.6% vs 3.5%, P = .485); heart failure (34.7% vs 38.9%, P = .655); or embolic events (41.7% vs 32.6%, P = .248). Indications for surgery (70.8% vs 70.8%; P = 1) and mortality (13.9% vs 16.7%; P = .741) were similar between groups. Conclusions. SAG endocarditis is an infrequent but serious condition that presents a prognosis similar to that of VGS/SGG.Financial support: This work was supported by Plan Nacional de I+D+i 2013‐2016 and Instituto de Salud Carlos III, Subdirección General de Redes y Centros de Investigación Cooperativa, Ministerio de Ciencia, Innovación y Universidades, Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0005), co‐financed by the European Development Regional Fund “A way to achieve Europe,” Operative Program Intelligent Growth 2014–2020. We thank CERCA Programme/Generalitat de Catalunya for institutional support. J. M. M. received a personal 80:20 research grant from Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain, during 2017–2021.Oxford University PressUniversidad de Cantabria20212021-03-29journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articlehttp://hdl.handle.net/10902/24994Open Forum Infectious Diseases, Volume 8, Issue 6, June 2021, ofab163reponame:UCrea Repositorio Abierto de la Universidad de Cantabriainstname:Universidad de Cantabria (UC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repositorio.unican.es:10902/249942026-06-02T12:39:31Z
dc.title.none.fl_str_mv Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study
title Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study
spellingShingle Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study
Escrihuela-Vidal, Francesc
Infective endocarditis
Streptococcus anginosus
Viridans group streptococci
Streptococcus gallolyticus
title_short Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study
title_full Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study
title_fullStr Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study
title_full_unstemmed Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study
title_sort Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study
dc.creator.none.fl_str_mv Escrihuela-Vidal, Francesc
López-Cortés, Luis Eduardo
Escolà-Vergé, Laura
Alarcón González, Arístides de
Cuervo, Guillermo
Sánchez-Porto, Antonio
Fernández-Hidalgo, Nuria
Luque, Rafael
Montejo, Miguel
Miró, José María
Goenaga, Miguel Ángel
Muñoz, Patricia
Valerio, Maricela
Ripa, Marco
Sousa-Regueiro, Dolores
Gurguí, Mercé
Fariñas Álvarez, María del Carmen
Mateu, Lourdes
García Vázquez, Elisa
Gálvez-Acebal, Juan
author Escrihuela-Vidal, Francesc
author_facet Escrihuela-Vidal, Francesc
López-Cortés, Luis Eduardo
Escolà-Vergé, Laura
Alarcón González, Arístides de
Cuervo, Guillermo
Sánchez-Porto, Antonio
Fernández-Hidalgo, Nuria
Luque, Rafael
Montejo, Miguel
Miró, José María
Goenaga, Miguel Ángel
Muñoz, Patricia
Valerio, Maricela
Ripa, Marco
Sousa-Regueiro, Dolores
Gurguí, Mercé
Fariñas Álvarez, María del Carmen
Mateu, Lourdes
García Vázquez, Elisa
Gálvez-Acebal, Juan
author_role author
author2 López-Cortés, Luis Eduardo
Escolà-Vergé, Laura
Alarcón González, Arístides de
Cuervo, Guillermo
Sánchez-Porto, Antonio
Fernández-Hidalgo, Nuria
Luque, Rafael
Montejo, Miguel
Miró, José María
Goenaga, Miguel Ángel
Muñoz, Patricia
Valerio, Maricela
Ripa, Marco
Sousa-Regueiro, Dolores
Gurguí, Mercé
Fariñas Álvarez, María del Carmen
Mateu, Lourdes
García Vázquez, Elisa
Gálvez-Acebal, Juan
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad de Cantabria
dc.subject.none.fl_str_mv Infective endocarditis
Streptococcus anginosus
Viridans group streptococci
Streptococcus gallolyticus
topic Infective endocarditis
Streptococcus anginosus
Viridans group streptococci
Streptococcus gallolyticus
description Background. Although Streptococcus anginosus group (SAG) endocarditis is considered a severe disease associated with abscess formation and embolic events, there is limited evidence to support this assumption. Methods. We performed a retrospective analysis of prospectively collected data from consecutive patients with definite SAG endocarditis in 28 centers in Spain and Italy. A comparison between cases due to SAG endocarditis and viridans group streptococci (VGS) or Streptococcus gallolyticus group (SGG) was performed in a 1:2 matched analysis. Results. Of 5336 consecutive cases of definite endocarditis, 72 (1.4%) were due to SAG and matched with 144 cases due to VGS/ SGG. SAG endocarditis was community acquired in 64 (88.9%) cases and affected aortic native valve in 29 (40.3%). When com paring SAG and VGS/SGG endocarditis, no significant differences were found in septic shock (8.3% vs 3.5%, P = .116); valve disorder, including perforation (22.2% vs 18.1%, P = .584), pseudoaneurysm (16.7% vs 8.3%, P = .108), or prosthesis dehiscence (1.4% vs 6.3%, P = .170); paravalvular complications, including abscess (25% vs 18.8%, P = .264) and intracardiac fistula (5.6% vs 3.5%, P = .485); heart failure (34.7% vs 38.9%, P = .655); or embolic events (41.7% vs 32.6%, P = .248). Indications for surgery (70.8% vs 70.8%; P = 1) and mortality (13.9% vs 16.7%; P = .741) were similar between groups. Conclusions. SAG endocarditis is an infrequent but serious condition that presents a prognosis similar to that of VGS/SGG.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-03-29
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10902/24994
url http://hdl.handle.net/10902/24994
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv Open Forum Infectious Diseases, Volume 8, Issue 6, June 2021, ofab163
reponame:UCrea Repositorio Abierto de la Universidad de Cantabria
instname:Universidad de Cantabria (UC)
instname_str Universidad de Cantabria (UC)
reponame_str UCrea Repositorio Abierto de la Universidad de Cantabria
collection UCrea Repositorio Abierto de la Universidad de Cantabria
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869423288500879360
score 15,300719

Similares en LA Referencia