Diagnostic delay and survival in squamous cell carcinoma of the oral cavity

The aim of this thesis was to identify the magnitude of the time intervals that define the pathway of the oral cancer patient from the beginning of the symptoms until diagnosis, and treatment, and to evaluate their impact on patients´ survival. For this purpose, we designed an observational survival...

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Detalles Bibliográficos
Autor: Otero Rico, Ana
Tipo de recurso: tesis doctoral
Fecha de publicación:2023
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/30575
Acceso en línea:http://hdl.handle.net/10347/30575
Access Level:acceso abierto
Palabra clave:Materias::Investigación::32 Ciencias médicas::3201 Ciencias clínicas::320101 Oncología
Materias::Investigación::32 Ciencias médicas::3213 Cirugía::321313 Ortodoncia-estomatología
Descripción
Sumario:The aim of this thesis was to identify the magnitude of the time intervals that define the pathway of the oral cancer patient from the beginning of the symptoms until diagnosis, and treatment, and to evaluate their impact on patients´ survival. For this purpose, we designed an observational survival study, with an ambispective component. In our study, the hospital interval was a relevant interval in the oral cancer patients´ pathway to treatment, representing a fourth of the overall interval, and showing a counterintuitive association, where those patients with short hospital intervals had significantly higher mortality, due to the waiting time paradox. Also, the overall time interval has shown a non-monotonic association with oral cancer mortality.