Supplementary information: Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions

Supplementary Figures S1-S9. -- Supplementary Files: o Supplementary Data 1 related to Figure 2. ifferentially expressed genes in the comparison of CA1 and DG nuRNA-seq samples (see attached Excel file, 1 sheet). o Supplementary Data 2 related to Figure 2. gProfiler GO analysis of DEGs upregulated i...

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Autores: Alaiz-Noya, Marta, Miozzo, Federico, Fuentes-Ramos, Miguel, Machnicka, Magdalena A., Kurowska, Marcelina, Herrera, Macarena, Blanco, Beatriz del, Niñerola, Sergio, Bustos-Martínez, Isabel, Wilczynski, Bartek, Barco, Ángel
Tipo de documento: conjunto de datos
Data de publicação:2025
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/412176
Acesso em linha:http://hdl.handle.net/10261/412176
Access Level:Acceso aberto
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spelling Supplementary information: Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditionsAlaiz-Noya, MartaMiozzo, FedericoFuentes-Ramos, MiguelMachnicka, Magdalena A.Kurowska, MarcelinaHerrera, MacarenaBlanco, Beatriz delNiñerola, SergioBustos-Martínez, IsabelWilczynski, BartekBarco, ÁngelSupplementary Figures S1-S9. -- Supplementary Files: o Supplementary Data 1 related to Figure 2. ifferentially expressed genes in the comparison of CA1 and DG nuRNA-seq samples (see attached Excel file, 1 sheet). o Supplementary Data 2 related to Figure 2. gProfiler GO analysis of DEGs upregulated in CA1 SC (A) and DG SC (B) (see attached Excel file, 2 sheets). o Supplementary Data 3 related to Figure 2. Differentially accessible regions in the comparison of CA1 and DG ATAC-seq samples and associated genes (see attached Excel file, 2 sheets). o Supplementary Data 4 relative to Figure 2. Differentially acetylated regions in the comparison of CA1 and DG H3K27ac CUT&TAG samples and associated genes (see attached Excel file, 2 sheets). o Supplementary Data 5 related to Figure 2. Differentially methylated regions in the comparison of CA1 and DG WGBS samples and associated genes (see attached Excel file, 2 sheets). o Supplementary Data 6 related to Figure 4. Differentially expressed genes in the comparison of EE/SC/IE nuRNA-seq samples (see attached Excel file, 2 sheets). o Supplementary Data 7 relative to Figure 5. Differentially accessible regions in the comparison of EE/SC/IE DG ATAC-seq samples and associated genes (see attached Excel file, 2 sheets). o Supplementary Data 8 relative to Figure 5. Differentially methylated regions in the comparison of EE/SC/IE WGBS samples and associated genes (see attached Excel file, 9 sheets). o Supplementary Data 9 related to Figure 6. Relationship between DEGs and chromatin changes (see attached Excel file, 2 sheets). o Supplementary Data 10 related to Figure 7. GO analysis of AP1 related genes (see attached Excel file, 3 sheets). o Supplementary Data 11 related to Methods. Sequencing depth and read alignment (see attached Excel file, 1 sheet).Peer reviewedSpringer NatureMiozzo, Federico [0000-0003-0818-9525]Barco, Ángel [0000-0002-0653-3751]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202620262025info:eu-repo/semantics/datasethttp://purl.org/coar/resource_type/c_ddb1application/pdfapplication/vnd.ms-excelhttp://hdl.handle.net/10261/412176reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésAlaiz-Noya, Marta; Miozzo, Federico; Fuentes-Ramos, Miguel; Machnicka, Magdalena A.; Kurowska, Marcelina; Herrera, Macarena; Blanco, Beatriz del; Niñerola, Sergio; Bustos-Martínez, Isabel; Wilczynski, Bartek; Barco, Ángel. Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions. https://doi.org/10.1038/s41467-025-65343-5. http://hdl.handle.net/10261/412156https://doi.org/10.1038/s41467-025-65343-5Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/4121762026-05-22T06:33:51Z
dc.title.none.fl_str_mv Supplementary information: Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions
title Supplementary information: Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions
spellingShingle Supplementary information: Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions
Alaiz-Noya, Marta
title_short Supplementary information: Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions
title_full Supplementary information: Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions
title_fullStr Supplementary information: Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions
title_full_unstemmed Supplementary information: Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions
title_sort Supplementary information: Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions
dc.creator.none.fl_str_mv Alaiz-Noya, Marta
Miozzo, Federico
Fuentes-Ramos, Miguel
Machnicka, Magdalena A.
Kurowska, Marcelina
Herrera, Macarena
Blanco, Beatriz del
Niñerola, Sergio
Bustos-Martínez, Isabel
Wilczynski, Bartek
Barco, Ángel
author Alaiz-Noya, Marta
author_facet Alaiz-Noya, Marta
Miozzo, Federico
Fuentes-Ramos, Miguel
Machnicka, Magdalena A.
Kurowska, Marcelina
Herrera, Macarena
Blanco, Beatriz del
Niñerola, Sergio
Bustos-Martínez, Isabel
Wilczynski, Bartek
Barco, Ángel
author_role author
author2 Miozzo, Federico
Fuentes-Ramos, Miguel
Machnicka, Magdalena A.
Kurowska, Marcelina
Herrera, Macarena
Blanco, Beatriz del
Niñerola, Sergio
Bustos-Martínez, Isabel
Wilczynski, Bartek
Barco, Ángel
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Miozzo, Federico [0000-0003-0818-9525]
Barco, Ángel [0000-0002-0653-3751]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
description Supplementary Figures S1-S9. -- Supplementary Files: o Supplementary Data 1 related to Figure 2. ifferentially expressed genes in the comparison of CA1 and DG nuRNA-seq samples (see attached Excel file, 1 sheet). o Supplementary Data 2 related to Figure 2. gProfiler GO analysis of DEGs upregulated in CA1 SC (A) and DG SC (B) (see attached Excel file, 2 sheets). o Supplementary Data 3 related to Figure 2. Differentially accessible regions in the comparison of CA1 and DG ATAC-seq samples and associated genes (see attached Excel file, 2 sheets). o Supplementary Data 4 relative to Figure 2. Differentially acetylated regions in the comparison of CA1 and DG H3K27ac CUT&TAG samples and associated genes (see attached Excel file, 2 sheets). o Supplementary Data 5 related to Figure 2. Differentially methylated regions in the comparison of CA1 and DG WGBS samples and associated genes (see attached Excel file, 2 sheets). o Supplementary Data 6 related to Figure 4. Differentially expressed genes in the comparison of EE/SC/IE nuRNA-seq samples (see attached Excel file, 2 sheets). o Supplementary Data 7 relative to Figure 5. Differentially accessible regions in the comparison of EE/SC/IE DG ATAC-seq samples and associated genes (see attached Excel file, 2 sheets). o Supplementary Data 8 relative to Figure 5. Differentially methylated regions in the comparison of EE/SC/IE WGBS samples and associated genes (see attached Excel file, 9 sheets). o Supplementary Data 9 related to Figure 6. Relationship between DEGs and chromatin changes (see attached Excel file, 2 sheets). o Supplementary Data 10 related to Figure 7. GO analysis of AP1 related genes (see attached Excel file, 3 sheets). o Supplementary Data 11 related to Methods. Sequencing depth and read alignment (see attached Excel file, 1 sheet).
publishDate 2025
dc.date.none.fl_str_mv 2025
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/dataset
http://purl.org/coar/resource_type/c_ddb1
format dataset
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/412176
url http://hdl.handle.net/10261/412176
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Alaiz-Noya, Marta; Miozzo, Federico; Fuentes-Ramos, Miguel; Machnicka, Magdalena A.; Kurowska, Marcelina; Herrera, Macarena; Blanco, Beatriz del; Niñerola, Sergio; Bustos-Martínez, Isabel; Wilczynski, Bartek; Barco, Ángel. Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions. https://doi.org/10.1038/s41467-025-65343-5. http://hdl.handle.net/10261/412156
https://doi.org/10.1038/s41467-025-65343-5
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/vnd.ms-excel
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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