Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysis

Producción Científica

Detalles Bibliográficos
Autores: Viribay, Aitor, Fernández Lázaro, Diego, Fernández Landa, Julen, Castañeda Babarro, Arkaitz, Sánchez Collado, Pilar, Mielgo Ayuso, Juan Francisco
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Universidad de Valladolid
Repositorio:UVaDOC. Repositorio Documental de la Universidad de Valladolid
OAI Identifier:oai:uvadoc.uva.es:10324/61151
Acceso en línea:https://doi.org/10.3390/nu14173479
https://uvadoc.uva.es/handle/10324/61151
Access Level:acceso abierto
Palabra clave:Nutrition
Sports - Physiological aspects
Athletes - Nutrition
Atletas - Nutrición
Food additives
Aditivos alimentarios
Nutrición - Alimentos
Dietetics
Nitric oxide
Oxido nitrico
Exercise
Ejercicio físico
Endurance sports
Deportes de resistencia
Meta-analysis
Citrulline
Citrulina
3104.06 Nutrición
2411.06 Fisiología del Ejercicio
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spelling Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysisViribay, AitorFernández Lázaro, DiegoFernández Landa, JulenCastañeda Babarro, ArkaitzSánchez Collado, PilarMielgo Ayuso, Juan FranciscoNutritionSports - Physiological aspectsAthletes - NutritionAtletas - NutriciónFood additivesAditivos alimentariosNutrición - AlimentosDieteticsNitric oxideOxido nitricoExerciseEjercicio físicoEndurance sportsDeportes de resistenciaMeta-analysisCitrullineCitrulina3104.06 Nutrición2411.06 Fisiología del EjercicioProducción CientíficaSupplementation with Citrulline (Cit) has been shown to have a positive impact on aerobic exercise performance and related outcomes such as lactate, oxygen uptake (VO2) kinetics, and the rate of perceived exertion (RPE), probably due to its relationship to endogenous nitric oxide production. However, current research has shown this to be controversial. The main objective of this systematic review and meta-analysis was to analyze and assess the effects of Cit supplementation on aerobic exercise performance and related outcomes, as well as to show the most suitable doses and timing of ingestion. A structured literature search was carried out by the PRISMA® (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and PICOS guidelines in the following databases: Pubmed/Medline, Scopus, and Web of Science (WOS). A total of 10 studies were included in the analysis, all of which exclusively compared the effects of Cit supplementation with those of a placebo group on aerobic performance, lactate, VO2, and the RPE. Those articles that used other supplements and measured other outcomes were excluded. The meta-analysis was carried out using Hedges’ g random effects model and pooled standardized mean differences (SMD). The results showed no positive effects of Cit supplementation on aerobic performance (pooled SMD = 0.15; 95% CI (−0.02 to 0.32); I2, 0%; p = 0.08), the RPE (pooled SMD = −0.03; 95% CI (−0.43 to 0.38); I2, 49%; p = 0.9), VO2 kinetics (pooled SMD = 0.01; 95% CI (−0.16 to 0.17); I2, 0%; p = 0.94), and lactate (pooled SMD = 0.25; 95% CI (−0.10 to 0.59); I2, 0%; p = 0.16). In conclusion, Cit supplementation did not prove to have any benefits for aerobic exercise performance and related outcomes. Where chronic protocols seemed to show a positive tendency, more studies in the field are needed to better understand the effects.MDPI2022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.3390/nu14173479https://uvadoc.uva.es/handle/10324/61151reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolidinstname:Universidad de ValladolidIngléshttps://www.mdpi.com/2072-6643/14/17/3479info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/oai:uvadoc.uva.es:10324/611512026-06-13T12:44:47Z
dc.title.none.fl_str_mv Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysis
title Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysis
spellingShingle Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysis
Viribay, Aitor
Nutrition
Sports - Physiological aspects
Athletes - Nutrition
Atletas - Nutrición
Food additives
Aditivos alimentarios
Nutrición - Alimentos
Dietetics
Nitric oxide
Oxido nitrico
Exercise
Ejercicio físico
Endurance sports
Deportes de resistencia
Meta-analysis
Citrulline
Citrulina
3104.06 Nutrición
2411.06 Fisiología del Ejercicio
title_short Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysis
title_full Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysis
title_fullStr Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysis
title_full_unstemmed Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysis
title_sort Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysis
dc.creator.none.fl_str_mv Viribay, Aitor
Fernández Lázaro, Diego
Fernández Landa, Julen
Castañeda Babarro, Arkaitz
Sánchez Collado, Pilar
Mielgo Ayuso, Juan Francisco
author Viribay, Aitor
author_facet Viribay, Aitor
Fernández Lázaro, Diego
Fernández Landa, Julen
Castañeda Babarro, Arkaitz
Sánchez Collado, Pilar
Mielgo Ayuso, Juan Francisco
author_role author
author2 Fernández Lázaro, Diego
Fernández Landa, Julen
Castañeda Babarro, Arkaitz
Sánchez Collado, Pilar
Mielgo Ayuso, Juan Francisco
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Nutrition
Sports - Physiological aspects
Athletes - Nutrition
Atletas - Nutrición
Food additives
Aditivos alimentarios
Nutrición - Alimentos
Dietetics
Nitric oxide
Oxido nitrico
Exercise
Ejercicio físico
Endurance sports
Deportes de resistencia
Meta-analysis
Citrulline
Citrulina
3104.06 Nutrición
2411.06 Fisiología del Ejercicio
topic Nutrition
Sports - Physiological aspects
Athletes - Nutrition
Atletas - Nutrición
Food additives
Aditivos alimentarios
Nutrición - Alimentos
Dietetics
Nitric oxide
Oxido nitrico
Exercise
Ejercicio físico
Endurance sports
Deportes de resistencia
Meta-analysis
Citrulline
Citrulina
3104.06 Nutrición
2411.06 Fisiología del Ejercicio
description Producción Científica
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.3390/nu14173479
https://uvadoc.uva.es/handle/10324/61151
url https://doi.org/10.3390/nu14173479
https://uvadoc.uva.es/handle/10324/61151
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://www.mdpi.com/2072-6643/14/17/3479
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname:Universidad de Valladolid
instname_str Universidad de Valladolid
reponame_str UVaDOC. Repositorio Documental de la Universidad de Valladolid
collection UVaDOC. Repositorio Documental de la Universidad de Valladolid
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300719

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