Exploring the self-assembly of cyclic peptides into multidimensional nanostructures

Self-assembly is a fundamental process whereby individual molecules spontaneously associate into well-defined structures. Nature employs self-assembly to create complex architectures with remarkable structural and functional precision. This natural sophistication has inspired scientists to rationall...

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Detalles Bibliográficos
Autor: Díaz Arias, Sandra Natalia
Tipo de recurso: tesis doctoral
Fecha de publicación:2024
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/37641
Acceso en línea:https://hdl.handle.net/10347/37641
Access Level:acceso abierto
Palabra clave:supramolecular chemistry
self-assembly
cyclic peptides
230618 Estructuras de las moléculas orgánicas
230699 Otras (especificar)
Descripción
Sumario:Self-assembly is a fundamental process whereby individual molecules spontaneously associate into well-defined structures. Nature employs self-assembly to create complex architectures with remarkable structural and functional precision. This natural sophistication has inspired scientists to rationally design synthetic analogues for the fabrication of structures and functions not evolved in nature. Despite important developments in this field, the design of synthetic molecules with hierarchical levels of self-assembly remains a challenging task. In this doctoral thesis, synthetic cyclic peptides are explored as customizable building blocks for the hierarchical self-assembly of multidimensional nanostructures. Key design principles are presented to direct hierarchical stages of selfassembly by rational molecular design.