Influence of Cellular Aging on Liver Stiffness in Patients With Hepatitis C Virus Achieving Sustained Viral Response

[Background] Liver stiffness (LS) is not reduced in 10%–30% of patients who achieve sustained viral response (SVR) after hepatitis C virus (HCV) elimination with direct-acting antivirals (DAA). Our aim was to analyze whether the parameters associated with cellular aging measured at the DAA initiatio...

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Detalles Bibliográficos
Autores: González-Serna, Alejandro, Corma-Gómez, Anaïs, Cano, Mercedes, Rubio-Sánchez, Ricardo, Martín-Sierra, Carmen, Rincón, Pilar, Martín-Carmona, Jesica, Pérez-García, Margarita, Pineda, Juan Antonio, Real, Luis Miguel, Macías, Juan
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/400697
Acceso en línea:http://hdl.handle.net/10261/400697
https://api.elsevier.com/content/abstract/scopus_id/105008110155
Access Level:acceso abierto
Palabra clave:DAA
SVR
Cellular aging
Liver stiffness
Telomere length
Descripción
Sumario:[Background] Liver stiffness (LS) is not reduced in 10%–30% of patients who achieve sustained viral response (SVR) after hepatitis C virus (HCV) elimination with direct-acting antivirals (DAA). Our aim was to analyze whether the parameters associated with cellular aging measured at the DAA initiation date are related to LS reduction upon achieving SVR.

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