Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study

Background: To assess the prenatal, early postnatal and adolescent factors associated with overweight/obesity (OwO) and other cardiometabolic risk factors at age 15. Methods: Longitudinal study based on 241 participants from the INMA-Valencia cohort. Z-scores of body mass index (zBMI), waist circumf...

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Autores: Lozano, M, Vallejo-Ortega, J, Marín, N, González-Safont, L, Esplugues, A, Lopez-Espinosa, MJ, Beneito, A, González-Palacios, S, Llop, S, Soler-Blasco, R
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p19163
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/19163
Access Level:acceso abierto
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spelling Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth studyLozano, MVallejo-Ortega, JMarín, NGonzález-Safont, LEsplugues, ALopez-Espinosa, MJBeneito, AGonzález-Palacios, SLlop, SSoler-Blasco, RBackground: To assess the prenatal, early postnatal and adolescent factors associated with overweight/obesity (OwO) and other cardiometabolic risk factors at age 15. Methods: Longitudinal study based on 241 participants from the INMA-Valencia cohort. Z-scores of body mass index (zBMI), waist circumference (zWC), and waist-to-height ratio (WHtR), systolic and diastolic BP (zSBP and zDBP) were evaluated at ages 4, 7, 9, 11 and 15. A cardiometabolic risk score was calculated. Covariates were collected at pregnancy, birth, and age 15. Results: At age 4, 30.7% presented overweight/obesity (zBMI > 1 SD), increasing to 46.1% at age 9, and decreasing to 29.3% at age 15 (29.3%). The proportion of high/excess central adiposity was lower than overweight/obesity at all ages. Adjusted models showed that pre-pregnancy obesity was positively associated with all cardiometabolic outcomes, except zSBP (i.e. beta [95% CI]: 0.77 [0.25, 1.29] for zBMI, and 2.31 [0.94, 3.69] for CMR score). Smoking during pregnancy was directly related to zSBP and zBMI. Adolescent physical activity was inversely associated with WHtR, zFM, zWC, zDBP and cardiometabolic risk scores (beta -0.65 [95% CI -0.95, -0.36]). Cereal intake and processed meat consumption were positively related to WHtR, zBMI and zWC. Conclusion: Early modifiable factors impact adolescent cardiometabolic health. This information could improve preventive interventions and policies from very early.SPRINGERNATURE2025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fisabio.portalinvestigacion.com/publicaciones/19163PEDIATRIC RESEARCHISSN: 00313998ISSNe: 15300447reponame:r-FISABIO. Repositorio Institucional de Producción Científicainstname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)Inglésinfo:eu-repo/semantics/openAccessoai:fisabio.fundanetsuite.com:p191632026-06-11T12:45:17Z
dc.title.none.fl_str_mv Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study
title Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study
spellingShingle Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study
Lozano, M
title_short Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study
title_full Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study
title_fullStr Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study
title_full_unstemmed Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study
title_sort Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study
dc.creator.none.fl_str_mv Lozano, M
Vallejo-Ortega, J
Marín, N
González-Safont, L
Esplugues, A
Lopez-Espinosa, MJ
Beneito, A
González-Palacios, S
Llop, S
Soler-Blasco, R
author Lozano, M
author_facet Lozano, M
Vallejo-Ortega, J
Marín, N
González-Safont, L
Esplugues, A
Lopez-Espinosa, MJ
Beneito, A
González-Palacios, S
Llop, S
Soler-Blasco, R
author_role author
author2 Vallejo-Ortega, J
Marín, N
González-Safont, L
Esplugues, A
Lopez-Espinosa, MJ
Beneito, A
González-Palacios, S
Llop, S
Soler-Blasco, R
author2_role author
author
author
author
author
author
author
author
author
description Background: To assess the prenatal, early postnatal and adolescent factors associated with overweight/obesity (OwO) and other cardiometabolic risk factors at age 15. Methods: Longitudinal study based on 241 participants from the INMA-Valencia cohort. Z-scores of body mass index (zBMI), waist circumference (zWC), and waist-to-height ratio (WHtR), systolic and diastolic BP (zSBP and zDBP) were evaluated at ages 4, 7, 9, 11 and 15. A cardiometabolic risk score was calculated. Covariates were collected at pregnancy, birth, and age 15. Results: At age 4, 30.7% presented overweight/obesity (zBMI > 1 SD), increasing to 46.1% at age 9, and decreasing to 29.3% at age 15 (29.3%). The proportion of high/excess central adiposity was lower than overweight/obesity at all ages. Adjusted models showed that pre-pregnancy obesity was positively associated with all cardiometabolic outcomes, except zSBP (i.e. beta [95% CI]: 0.77 [0.25, 1.29] for zBMI, and 2.31 [0.94, 3.69] for CMR score). Smoking during pregnancy was directly related to zSBP and zBMI. Adolescent physical activity was inversely associated with WHtR, zFM, zWC, zDBP and cardiometabolic risk scores (beta -0.65 [95% CI -0.95, -0.36]). Cereal intake and processed meat consumption were positively related to WHtR, zBMI and zWC. Conclusion: Early modifiable factors impact adolescent cardiometabolic health. This information could improve preventive interventions and policies from very early.
publishDate 2025
dc.date.none.fl_str_mv 2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fisabio.portalinvestigacion.com/publicaciones/19163
url https://fisabio.portalinvestigacion.com/publicaciones/19163
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv SPRINGERNATURE
publisher.none.fl_str_mv SPRINGERNATURE
dc.source.none.fl_str_mv PEDIATRIC RESEARCH
ISSN: 00313998
ISSNe: 15300447
reponame:r-FISABIO. Repositorio Institucional de Producción Científica
instname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
instname_str Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
reponame_str r-FISABIO. Repositorio Institucional de Producción Científica
collection r-FISABIO. Repositorio Institucional de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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