Fructose induces synthesis and reduces oxidation of liver fatty acids through ChREBP activation

Introduction and aims. During last few decades, the prevalence of obesity, metabolic syndrome and insulin resistance, among other metabolic disturbances, has raised considerably in many countries worldwide. Environmental factors (diet, physical activity), in tandem with predisposing genetic factors,...

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Detalhes bibliográficos
Autores: Rebollo de Grado, Alba, Baena Muñoz, Miguel, Roglans i Ribas, Núria, Alegret i Jordà, Marta, Laguna Egea, Juan Carlos
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2012
País:España
Recursos:Universidad de Barcelona
Repositório:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/51004
Acesso em linha:https://hdl.handle.net/2445/51004
Access Level:Acceso aberto
Palavra-chave:Fructosa
Malalties del fetge
Àcids grassos
Fructose
Liver diseases
Fatty acids
Descrição
Resumo:Introduction and aims. During last few decades, the prevalence of obesity, metabolic syndrome and insulin resistance, among other metabolic disturbances, has raised considerably in many countries worldwide. Environmental factors (diet, physical activity), in tandem with predisposing genetic factors, may be responsible for this trend. Along with an increase in total energy consumption during recent decades, there has also been a shift in the type of nutrients, with an increased consumption of fructose, largely attributable to a greater intake of beverages containing high levels of fructose...