Fructose induces synthesis and reduces oxidation of liver fatty acids through ChREBP activation

Introduction and aims. During last few decades, the prevalence of obesity, metabolic syndrome and insulin resistance, among other metabolic disturbances, has raised considerably in many countries worldwide. Environmental factors (diet, physical activity), in tandem with predisposing genetic factors,...

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Detalles Bibliográficos
Autores: Rebollo de Grado, Alba, Baena Muñoz, Miguel, Roglans i Ribas, Núria, Alegret i Jordà, Marta, Laguna Egea, Juan Carlos
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/51004
Acceso en línea:https://hdl.handle.net/2445/51004
Access Level:acceso abierto
Palabra clave:Fructosa
Malalties del fetge
Àcids grassos
Fructose
Liver diseases
Fatty acids
Descripción
Sumario:Introduction and aims. During last few decades, the prevalence of obesity, metabolic syndrome and insulin resistance, among other metabolic disturbances, has raised considerably in many countries worldwide. Environmental factors (diet, physical activity), in tandem with predisposing genetic factors, may be responsible for this trend. Along with an increase in total energy consumption during recent decades, there has also been a shift in the type of nutrients, with an increased consumption of fructose, largely attributable to a greater intake of beverages containing high levels of fructose...