Fungal phylogenomics.A global analysis of fungal genomes and their evolution
Fungi is the eukaryotic group with a largest amount of completely sequenced species and therefore it is particularly well suited for comparative genomics analyses. <br/>A species tree is often an important part of phylogenomics analysis. Concern about its reliability led us to design several m...
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| Tipo de recurso: | tesis doctoral |
| Estado: | Versión publicada |
| Fecha de publicación: | 2010 |
| País: | España |
| Institución: | CBUC, CESCA |
| Repositorio: | TDR. Tesis Doctorales en Red |
| OAI Identifier: | oai:www.tdx.cat:10803/8685 |
| Acceso en línea: | http://www.tdx.cat/TDX-1013110-154831 http://hdl.handle.net/10803/8685 |
| Access Level: | acceso abierto |
| Palabra clave: | Arbre de les espècies Fongs Transferència horitzontal de gens Filofenòmica 577 579 |
| Sumario: | Fungi is the eukaryotic group with a largest amount of completely sequenced species and therefore it is particularly well suited for comparative genomics analyses. <br/>A species tree is often an important part of phylogenomics analysis. Concern about its reliability led us to design several methods by which we could identify nodes in the species tree that were poorly supported by a whole phylome. We determined that the species tree was mostly well supported but some nodes showed large discrepancies to most genes.<br/>These results could partly be attributed to evolutionary events that result in topological changes in gene trees. Our analyses have shown that HGT plays an important role in fungal evolution. Gene duplications followed by differential loss are also often the cause of incongruence. The OXPHOS pathway, despite being formed by multi-protein complexes, has been affected by this process at similar levels than the rest of the genome. |
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