The impact of duration of illness on treatment nonresponse and drop-out

Objective: There are no generally accepted definitions or markers of treatment nonresponse in eating disorders (EDs). The aim of this paper was to examine how the duration of illness and other potential prognostic markers impacted on nonresponse and drop-out from treatment across different EDs subty...

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Authors: Fernández Aranda, Fernando|||0000-0002-2968-9898, Treasure, Janet|||0000-0003-0871-4596, Paslakis, Georgios|||0000-0002-2069-0024, Agüera, Zaida|||0000-0003-4453-4939, Giménez, Mónica|||0000-0003-2757-0145, Granero, Roser|||0000-0001-6308-3198, Sánchez Díaz, Isabel María|||0000-0001-5874-8204, Serrano-Troncoso, Eduardo|||0000-0002-4935-7348, Gorwood, Philip|||0000-0003-1845-3676, Herpertz-Dahlmann, Beate|||0000-0001-8450-3323, Bonin, Eva-Maria|||0000-0001-9123-9217, Monteleone, Palmiero|||0000-0002-5287-3829, Jiménez Murcia, Susana|||0000-0002-3596-8033
Format: article
Publication Date:2021
Country:España
Institution:Universitat Autònoma de Barcelona
Repository:Dipòsit Digital de Documents de la UAB
Language:English
OAI Identifier:oai:ddd.uab.cat:301990
Online Access:https://ddd.uab.cat/record/301990
https://dx.doi.org/urn:doi:10.1002/erv.2822
Access Level:Open access
Keyword:Anorexia nervosa
Binge eating disorder
Bulimia nervosa
Drop-out
Enduring
Other specified feeding and eating disorders
Treatment nonresponders
SDG 3 - Good Health and Well-being
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spelling The impact of duration of illness on treatment nonresponse and drop-outExploring the relevance of enduring eating disorder conceptFernández Aranda, Fernando|||0000-0002-2968-9898Treasure, Janet|||0000-0003-0871-4596Paslakis, Georgios|||0000-0002-2069-0024Agüera, Zaida|||0000-0003-4453-4939Giménez, Mónica|||0000-0003-2757-0145Granero, Roser|||0000-0001-6308-3198Sánchez Díaz, Isabel María|||0000-0001-5874-8204Serrano-Troncoso, Eduardo|||0000-0002-4935-7348Gorwood, Philip|||0000-0003-1845-3676Herpertz-Dahlmann, Beate|||0000-0001-8450-3323Bonin, Eva-Maria|||0000-0001-9123-9217Monteleone, Palmiero|||0000-0002-5287-3829Jiménez Murcia, Susana|||0000-0002-3596-8033Anorexia nervosaBinge eating disorderBulimia nervosaDrop-outEnduringOther specified feeding and eating disordersTreatment nonrespondersSDG 3 - Good Health and Well-beingObjective: There are no generally accepted definitions or markers of treatment nonresponse in eating disorders (EDs). The aim of this paper was to examine how the duration of illness and other potential prognostic markers impacted on nonresponse and drop-out from treatment across different EDs subtypes. Methods: A total sample of 1199 consecutively treated patients with EDs, according to Diagnostic and Statistical Manual of Mental Disorders, fifth edition criteria, participated in this study. Kaplan-Meier curves were calculated for each ED diagnosis in which the probability of recovery was plotted against the duration of illness. Results: Full remission was more likely for people with binge eating disorder (BED; 47.4%) and anorexia nervosa (AN; 43.9%) compared to bulimia nervosa (BN; 25.2%) and other specified feeding and EDs (OSFED; 23.2%). The cut-off points for the duration of the illness related with high likelihoods of poor response was 6-8 years among OSFED, 12-14 years among AN and BN and 20-21 years among BED. Other variables predicting nonresponse included dysfunctional personality traits. Conclusions: Nonresponse to treatment is associated with duration of illness which is in turn associated with poor response to previous treatment. However, there was no evidence for staging the illness using specific duration of illness criteria. Nevertheless, the shorter temporal trajectory for OSFED suggests that early interventions may be of importance for this group. 22021-01-0120212021-01-01Articlehttp://purl.org/coar/resource_type/c_6501AMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/301990https://dx.doi.org/urn:doi:10.1002/erv.2822reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets.https://rightsstatements.org/vocab/InC/1.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3019902026-06-06T12:50:31Z
dc.title.none.fl_str_mv The impact of duration of illness on treatment nonresponse and drop-out
Exploring the relevance of enduring eating disorder concept
title The impact of duration of illness on treatment nonresponse and drop-out
spellingShingle The impact of duration of illness on treatment nonresponse and drop-out
Fernández Aranda, Fernando|||0000-0002-2968-9898
Anorexia nervosa
Binge eating disorder
Bulimia nervosa
Drop-out
Enduring
Other specified feeding and eating disorders
Treatment nonresponders
SDG 3 - Good Health and Well-being
title_short The impact of duration of illness on treatment nonresponse and drop-out
title_full The impact of duration of illness on treatment nonresponse and drop-out
title_fullStr The impact of duration of illness on treatment nonresponse and drop-out
title_full_unstemmed The impact of duration of illness on treatment nonresponse and drop-out
title_sort The impact of duration of illness on treatment nonresponse and drop-out
dc.creator.none.fl_str_mv Fernández Aranda, Fernando|||0000-0002-2968-9898
Treasure, Janet|||0000-0003-0871-4596
Paslakis, Georgios|||0000-0002-2069-0024
Agüera, Zaida|||0000-0003-4453-4939
Giménez, Mónica|||0000-0003-2757-0145
Granero, Roser|||0000-0001-6308-3198
Sánchez Díaz, Isabel María|||0000-0001-5874-8204
Serrano-Troncoso, Eduardo|||0000-0002-4935-7348
Gorwood, Philip|||0000-0003-1845-3676
Herpertz-Dahlmann, Beate|||0000-0001-8450-3323
Bonin, Eva-Maria|||0000-0001-9123-9217
Monteleone, Palmiero|||0000-0002-5287-3829
Jiménez Murcia, Susana|||0000-0002-3596-8033
author Fernández Aranda, Fernando|||0000-0002-2968-9898
author_facet Fernández Aranda, Fernando|||0000-0002-2968-9898
Treasure, Janet|||0000-0003-0871-4596
Paslakis, Georgios|||0000-0002-2069-0024
Agüera, Zaida|||0000-0003-4453-4939
Giménez, Mónica|||0000-0003-2757-0145
Granero, Roser|||0000-0001-6308-3198
Sánchez Díaz, Isabel María|||0000-0001-5874-8204
Serrano-Troncoso, Eduardo|||0000-0002-4935-7348
Gorwood, Philip|||0000-0003-1845-3676
Herpertz-Dahlmann, Beate|||0000-0001-8450-3323
Bonin, Eva-Maria|||0000-0001-9123-9217
Monteleone, Palmiero|||0000-0002-5287-3829
Jiménez Murcia, Susana|||0000-0002-3596-8033
author_role author
author2 Treasure, Janet|||0000-0003-0871-4596
Paslakis, Georgios|||0000-0002-2069-0024
Agüera, Zaida|||0000-0003-4453-4939
Giménez, Mónica|||0000-0003-2757-0145
Granero, Roser|||0000-0001-6308-3198
Sánchez Díaz, Isabel María|||0000-0001-5874-8204
Serrano-Troncoso, Eduardo|||0000-0002-4935-7348
Gorwood, Philip|||0000-0003-1845-3676
Herpertz-Dahlmann, Beate|||0000-0001-8450-3323
Bonin, Eva-Maria|||0000-0001-9123-9217
Monteleone, Palmiero|||0000-0002-5287-3829
Jiménez Murcia, Susana|||0000-0002-3596-8033
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Anorexia nervosa
Binge eating disorder
Bulimia nervosa
Drop-out
Enduring
Other specified feeding and eating disorders
Treatment nonresponders
SDG 3 - Good Health and Well-being
topic Anorexia nervosa
Binge eating disorder
Bulimia nervosa
Drop-out
Enduring
Other specified feeding and eating disorders
Treatment nonresponders
SDG 3 - Good Health and Well-being
description Objective: There are no generally accepted definitions or markers of treatment nonresponse in eating disorders (EDs). The aim of this paper was to examine how the duration of illness and other potential prognostic markers impacted on nonresponse and drop-out from treatment across different EDs subtypes. Methods: A total sample of 1199 consecutively treated patients with EDs, according to Diagnostic and Statistical Manual of Mental Disorders, fifth edition criteria, participated in this study. Kaplan-Meier curves were calculated for each ED diagnosis in which the probability of recovery was plotted against the duration of illness. Results: Full remission was more likely for people with binge eating disorder (BED; 47.4%) and anorexia nervosa (AN; 43.9%) compared to bulimia nervosa (BN; 25.2%) and other specified feeding and EDs (OSFED; 23.2%). The cut-off points for the duration of the illness related with high likelihoods of poor response was 6-8 years among OSFED, 12-14 years among AN and BN and 20-21 years among BED. Other variables predicting nonresponse included dysfunctional personality traits. Conclusions: Nonresponse to treatment is associated with duration of illness which is in turn associated with poor response to previous treatment. However, there was no evidence for staging the illness using specific duration of illness criteria. Nevertheless, the shorter temporal trajectory for OSFED suggests that early interventions may be of importance for this group.
publishDate 2021
dc.date.none.fl_str_mv 2
2021-01-01
2021
2021-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
AM
http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/301990
https://dx.doi.org/urn:doi:10.1002/erv.2822
url https://ddd.uab.cat/record/301990
https://dx.doi.org/urn:doi:10.1002/erv.2822
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://rightsstatements.org/vocab/InC/1.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://rightsstatements.org/vocab/InC/1.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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