The impact of duration of illness on treatment nonresponse and drop-out

Objective: There are no generally accepted definitions or markers of treatment nonresponse in eating disorders (EDs). The aim of this paper was to examine how the duration of illness and other potential prognostic markers impacted on nonresponse and drop-out from treatment across different EDs subty...

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Detalhes bibliográficos
Autores: Fernández Aranda, Fernando|||0000-0002-2968-9898, Treasure, Janet|||0000-0003-0871-4596, Paslakis, Georgios|||0000-0002-2069-0024, Agüera, Zaida|||0000-0003-4453-4939, Giménez, Mónica|||0000-0003-2757-0145, Granero, Roser|||0000-0001-6308-3198, Sánchez Díaz, Isabel María|||0000-0001-5874-8204, Serrano-Troncoso, Eduardo|||0000-0002-4935-7348, Gorwood, Philip|||0000-0003-1845-3676, Herpertz-Dahlmann, Beate|||0000-0001-8450-3323, Bonin, Eva-Maria|||0000-0001-9123-9217, Monteleone, Palmiero|||0000-0002-5287-3829, Jiménez Murcia, Susana|||0000-0002-3596-8033
Formato: artículo
Fecha de publicación:2021
País:España
Recursos:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:301990
Acesso em linha:https://ddd.uab.cat/record/301990
https://dx.doi.org/urn:doi:10.1002/erv.2822
Access Level:acceso abierto
Palavra-chave:Anorexia nervosa
Binge eating disorder
Bulimia nervosa
Drop-out
Enduring
Other specified feeding and eating disorders
Treatment nonresponders
SDG 3 - Good Health and Well-being
Descrição
Resumo:Objective: There are no generally accepted definitions or markers of treatment nonresponse in eating disorders (EDs). The aim of this paper was to examine how the duration of illness and other potential prognostic markers impacted on nonresponse and drop-out from treatment across different EDs subtypes. Methods: A total sample of 1199 consecutively treated patients with EDs, according to Diagnostic and Statistical Manual of Mental Disorders, fifth edition criteria, participated in this study. Kaplan-Meier curves were calculated for each ED diagnosis in which the probability of recovery was plotted against the duration of illness. Results: Full remission was more likely for people with binge eating disorder (BED; 47.4%) and anorexia nervosa (AN; 43.9%) compared to bulimia nervosa (BN; 25.2%) and other specified feeding and EDs (OSFED; 23.2%). The cut-off points for the duration of the illness related with high likelihoods of poor response was 6-8 years among OSFED, 12-14 years among AN and BN and 20-21 years among BED. Other variables predicting nonresponse included dysfunctional personality traits. Conclusions: Nonresponse to treatment is associated with duration of illness which is in turn associated with poor response to previous treatment. However, there was no evidence for staging the illness using specific duration of illness criteria. Nevertheless, the shorter temporal trajectory for OSFED suggests that early interventions may be of importance for this group.