Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects
Scope Hydroxytyrosol (HT) is the major phenolic compound in virgin olive oil (VOO) in both free and complex forms (secoiridoids; SEC). Proteomics of cardiovascular tissues such as aorta or heart represents a promising tool to uncover the mechanisms of action of phenolic compounds in healthy animals.
| Autores: | , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2016 |
| País: | España |
| Institución: | Universitat de Lleida (UdL) |
| Repositorio: | Repositori Obert UdL |
| OAI Identifier: | oai:repositori.udl.cat:10459.1/59140 |
| Acceso en línea: | https://doi.org/10.1002/mnfr.201600052 http://hdl.handle.net/10459.1/59140 |
| Access Level: | acceso abierto |
| Palabra clave: | Cardiovascular disease Hydroxytyrosol Healthy rats Proteome Secoiridoids |
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Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effectsCatalán Santos, ÚrsulaRubió Piqué, LauraLópez de las Hazas Mingo, María del CarmenHerrero, PolNadal, PedroCanela, NúriaPedret, AnnaMotilva Casado, Mª JoséCardiovascular diseaseHydroxytyrosolHealthy ratsProteomeSecoiridoidsScope Hydroxytyrosol (HT) is the major phenolic compound in virgin olive oil (VOO) in both free and complex forms (secoiridoids; SEC). Proteomics of cardiovascular tissues such as aorta or heart represents a promising tool to uncover the mechanisms of action of phenolic compounds in healthy animals.Ú.C., L.R., M.-C.L., M.-J.M., and R.S. conceived and designed the experiments. M.-C.L. conducted the experiments. Ú.C., M.-C.L., and L.R. acquired the data. P.H., P.N., and N.C. processed the samples. Ú.C. and L.R. analyzed and interpreted the data. Ú.C., L.R., and P.H. drafted the article. Ú.C., L.R., M.-C.L., M.-J.M., and R.S. revising the article critically for important intellectual content. This study was supported by the Spanish Ministry of Education and Science, The MEFOPC Project (AGL2012-40144-C03-03 and AGL2012-40144-C03-02) and by the University of Lleida through the M-C. López de las Hazas grant.Wiley online library2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionhttps://doi.org/10.1002/mnfr.201600052http://hdl.handle.net/10459.1/59140reponame:Repositori Obert UdL instname:Universitat de Lleida (UdL)InglésMICINN/PN2008-2011/AGL2012-40144-C03-02MICINN/PN2008-2011/AGL2012-40144-C03-03Versió postprint del document publicat a https://doi.org/10.1002/mnfr.201600052Molecular Nutrition & Food Research, 2016, vol. 60, núm. 10, p. 2114–2129(c) WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2016info:eu-repo/semantics/openAccessoai:repositori.udl.cat:10459.1/591402026-06-24T12:42:17Z |
| dc.title.none.fl_str_mv |
Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects |
| title |
Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects |
| spellingShingle |
Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects Catalán Santos, Úrsula Cardiovascular disease Hydroxytyrosol Healthy rats Proteome Secoiridoids |
| title_short |
Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects |
| title_full |
Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects |
| title_fullStr |
Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects |
| title_full_unstemmed |
Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects |
| title_sort |
Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects |
| dc.creator.none.fl_str_mv |
Catalán Santos, Úrsula Rubió Piqué, Laura López de las Hazas Mingo, María del Carmen Herrero, Pol Nadal, Pedro Canela, Núria Pedret, Anna Motilva Casado, Mª José |
| author |
Catalán Santos, Úrsula |
| author_facet |
Catalán Santos, Úrsula Rubió Piqué, Laura López de las Hazas Mingo, María del Carmen Herrero, Pol Nadal, Pedro Canela, Núria Pedret, Anna Motilva Casado, Mª José |
| author_role |
author |
| author2 |
Rubió Piqué, Laura López de las Hazas Mingo, María del Carmen Herrero, Pol Nadal, Pedro Canela, Núria Pedret, Anna Motilva Casado, Mª José |
| author2_role |
author author author author author author author |
| dc.subject.none.fl_str_mv |
Cardiovascular disease Hydroxytyrosol Healthy rats Proteome Secoiridoids |
| topic |
Cardiovascular disease Hydroxytyrosol Healthy rats Proteome Secoiridoids |
| description |
Scope Hydroxytyrosol (HT) is the major phenolic compound in virgin olive oil (VOO) in both free and complex forms (secoiridoids; SEC). Proteomics of cardiovascular tissues such as aorta or heart represents a promising tool to uncover the mechanisms of action of phenolic compounds in healthy animals. |
| publishDate |
2016 |
| dc.date.none.fl_str_mv |
2016 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion |
| format |
article |
| status_str |
acceptedVersion |
| dc.identifier.none.fl_str_mv |
https://doi.org/10.1002/mnfr.201600052 http://hdl.handle.net/10459.1/59140 |
| url |
https://doi.org/10.1002/mnfr.201600052 http://hdl.handle.net/10459.1/59140 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
MICINN/PN2008-2011/AGL2012-40144-C03-02 MICINN/PN2008-2011/AGL2012-40144-C03-03 Versió postprint del document publicat a https://doi.org/10.1002/mnfr.201600052 Molecular Nutrition & Food Research, 2016, vol. 60, núm. 10, p. 2114–2129 |
| dc.rights.none.fl_str_mv |
(c) WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2016 info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
(c) WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2016 |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Wiley online library |
| publisher.none.fl_str_mv |
Wiley online library |
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reponame:Repositori Obert UdL instname:Universitat de Lleida (UdL) |
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Universitat de Lleida (UdL) |
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Repositori Obert UdL |
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Repositori Obert UdL |
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15.811543 |