Risk of all-cause mortality associated with chronic obstructive pulmonary disease and the role of healthy ageing trajectories: a population-based study of middle-aged and older adults

Objectives The aims were to study the risk of all-cause mortality associated with chronic obstructive pulmonary disease (COPD) and healthy ageing trajectories (HAT) in three birth cohorts and to determine the moderating role of HAT in the association between COPD and all-cause mortality. Design Pros...

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Detalles Bibliográficos
Autores: Bayés Marín, Ivet, Sánchez Niubó, Albert, Fernández Martínez, Daniel|||0000-0003-0012-2094, Haro, Josep Maria, Olaya, Beatriz
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/351001
Acceso en línea:https://hdl.handle.net/2117/351001
https://dx.doi.org/10.1136/bmjopen-2021-050947
Access Level:acceso abierto
Palabra clave:Medical statistics
Lungs -- Diseases, Obstructive -- Statistics
Estadística mèdica
Pulmons -- Malalties obstructives -- Estadístiques
Àrees temàtiques de la UPC::Matemàtiques i estadística::Estadística aplicada::Estadística biosanitària
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repository_id_str
spelling Risk of all-cause mortality associated with chronic obstructive pulmonary disease and the role of healthy ageing trajectories: a population-based study of middle-aged and older adultsBayés Marín, IvetSánchez Niubó, AlbertFernández Martínez, Daniel|||0000-0003-0012-2094Haro, Josep MariaOlaya, BeatrizMedical statisticsLungs -- Diseases, Obstructive -- StatisticsEstadística mèdicaPulmons -- Malalties obstructives -- EstadístiquesÀrees temàtiques de la UPC::Matemàtiques i estadística::Estadística aplicada::Estadística biosanitàriaObjectives The aims were to study the risk of all-cause mortality associated with chronic obstructive pulmonary disease (COPD) and healthy ageing trajectories (HAT) in three birth cohorts and to determine the moderating role of HAT in the association between COPD and all-cause mortality. Design Prospective cohort study. Setting Data from waves 1 to 5 of The Survey of Health, Ageing and Retirement in Europe. Participants The total sample was 28 857 community-dwelling individuals aged 50+ years. Main outcome All-cause mortality associated with COPD and HAT adjusting for covariates. We performed Aalen additive hazards models to explore these associations. Interactions between COPD and HAT were also explored. Analyses were conducted separately in three birth cohorts (>1945, 1936–1945 and =1935). Latent class growth analysis was used to classify participants into HAT. Results Three parallel HAT were found in the three birth cohorts (‘low’, ‘medium’ and ‘high’ healthy ageing). Participants with COPD had an increased mortality risk, but this effect was no longer significant after adjusting for covariates. The ‘low’ HAT was associated with increased mortality risk in the three subsamples, although this effect was lower after adjustment. The interaction between COPD and HAT was significant only in the =1935 birth cohort, indicating that those with COPD and a ‘low’ trajectory had a greater risk of mortality. Conclusions The healthy ageing scale may be a suitable tool to identify patients at higher risk to mitigate disease burden and improve patients’ quality of life.Peer Reviewed20212021-07-0120212021-09-10journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/351001https://dx.doi.org/10.1136/bmjopen-2021-050947reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/3510012026-05-27T15:37:01Z
dc.title.none.fl_str_mv Risk of all-cause mortality associated with chronic obstructive pulmonary disease and the role of healthy ageing trajectories: a population-based study of middle-aged and older adults
title Risk of all-cause mortality associated with chronic obstructive pulmonary disease and the role of healthy ageing trajectories: a population-based study of middle-aged and older adults
spellingShingle Risk of all-cause mortality associated with chronic obstructive pulmonary disease and the role of healthy ageing trajectories: a population-based study of middle-aged and older adults
Bayés Marín, Ivet
Medical statistics
Lungs -- Diseases, Obstructive -- Statistics
Estadística mèdica
Pulmons -- Malalties obstructives -- Estadístiques
Àrees temàtiques de la UPC::Matemàtiques i estadística::Estadística aplicada::Estadística biosanitària
title_short Risk of all-cause mortality associated with chronic obstructive pulmonary disease and the role of healthy ageing trajectories: a population-based study of middle-aged and older adults
title_full Risk of all-cause mortality associated with chronic obstructive pulmonary disease and the role of healthy ageing trajectories: a population-based study of middle-aged and older adults
title_fullStr Risk of all-cause mortality associated with chronic obstructive pulmonary disease and the role of healthy ageing trajectories: a population-based study of middle-aged and older adults
title_full_unstemmed Risk of all-cause mortality associated with chronic obstructive pulmonary disease and the role of healthy ageing trajectories: a population-based study of middle-aged and older adults
title_sort Risk of all-cause mortality associated with chronic obstructive pulmonary disease and the role of healthy ageing trajectories: a population-based study of middle-aged and older adults
dc.creator.none.fl_str_mv Bayés Marín, Ivet
Sánchez Niubó, Albert
Fernández Martínez, Daniel|||0000-0003-0012-2094
Haro, Josep Maria
Olaya, Beatriz
author Bayés Marín, Ivet
author_facet Bayés Marín, Ivet
Sánchez Niubó, Albert
Fernández Martínez, Daniel|||0000-0003-0012-2094
Haro, Josep Maria
Olaya, Beatriz
author_role author
author2 Sánchez Niubó, Albert
Fernández Martínez, Daniel|||0000-0003-0012-2094
Haro, Josep Maria
Olaya, Beatriz
author2_role author
author
author
author
dc.subject.none.fl_str_mv Medical statistics
Lungs -- Diseases, Obstructive -- Statistics
Estadística mèdica
Pulmons -- Malalties obstructives -- Estadístiques
Àrees temàtiques de la UPC::Matemàtiques i estadística::Estadística aplicada::Estadística biosanitària
topic Medical statistics
Lungs -- Diseases, Obstructive -- Statistics
Estadística mèdica
Pulmons -- Malalties obstructives -- Estadístiques
Àrees temàtiques de la UPC::Matemàtiques i estadística::Estadística aplicada::Estadística biosanitària
description Objectives The aims were to study the risk of all-cause mortality associated with chronic obstructive pulmonary disease (COPD) and healthy ageing trajectories (HAT) in three birth cohorts and to determine the moderating role of HAT in the association between COPD and all-cause mortality. Design Prospective cohort study. Setting Data from waves 1 to 5 of The Survey of Health, Ageing and Retirement in Europe. Participants The total sample was 28 857 community-dwelling individuals aged 50+ years. Main outcome All-cause mortality associated with COPD and HAT adjusting for covariates. We performed Aalen additive hazards models to explore these associations. Interactions between COPD and HAT were also explored. Analyses were conducted separately in three birth cohorts (>1945, 1936–1945 and =1935). Latent class growth analysis was used to classify participants into HAT. Results Three parallel HAT were found in the three birth cohorts (‘low’, ‘medium’ and ‘high’ healthy ageing). Participants with COPD had an increased mortality risk, but this effect was no longer significant after adjusting for covariates. The ‘low’ HAT was associated with increased mortality risk in the three subsamples, although this effect was lower after adjustment. The interaction between COPD and HAT was significant only in the =1935 birth cohort, indicating that those with COPD and a ‘low’ trajectory had a greater risk of mortality. Conclusions The healthy ageing scale may be a suitable tool to identify patients at higher risk to mitigate disease burden and improve patients’ quality of life.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-07-01
2021
2021-09-10
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/351001
https://dx.doi.org/10.1136/bmjopen-2021-050947
url https://hdl.handle.net/2117/351001
https://dx.doi.org/10.1136/bmjopen-2021-050947
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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