Epidemiology of heart failure with preserved ejection fraction: Results from the RICA Registry

Introduction and objectives: There is great interest in better characterizing patients with heart failure (HF) with preserved ejection fraction (HF-PEF). The objective of this study is to determine the prevalence, progression over time and to describe the clinical and epidemiological characteristics...

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Autores: Trullas, JC, Perez-Calvo, JI, Conde-Martel, A, Iborra, PL, Pedreira, IS, Ormaechea, G, Rangel, LS, Franco, AG, Cepeda, JM, Montero-Perez-Barquer, M, representacion Investigadores
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p12026
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/12026
Access Level:acceso abierto
Palabra clave:Heart failure
Diastolic
Stroke volume
Epidemiology
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spelling Epidemiology of heart failure with preserved ejection fraction: Results from the RICA RegistryTrullas, JCPerez-Calvo, JIConde-Martel, AIborra, PLPedreira, ISOrmaechea, GRangel, LSFranco, AGCepeda, JMMontero-Perez-Barquer, Mrepresentacion InvestigadoresHeart failureDiastolicStroke volumeEpidemiologyIntroduction and objectives: There is great interest in better characterizing patients with heart failure (HF) with preserved ejection fraction (HF-PEF). The objective of this study is to determine the prevalence, progression over time and to describe the clinical and epidemiological characteristics of patients with HF-PEF. Methods: From the National Registry of Heart Failure (RICA, prospective multicentre cohort study) we analysed patients consecutively admitted for HF in Internal Medicine wards over a period of 11 years (2008-2018). Results: 4752 patients were included, 2957 (62.2%) with preserved ejection fraction. This prevalence Introduction and objectives: There is great interest in better characterizing patients with heart failure (HF) with preserved ejection fraction (HF-PEF). The objective of this study is to determine the prevalence, progression over time and to describe the clinical and epidemiological characteristics of patients with HF-PEF. Methods: From the National Registry of Heart Failure (RICA, prospective multicentre cohort study) we analysed patients consecutively admitted for HF in Internal Medicine wards over a period of 11 years (2008-2018). Results: 4752 patients were included, 2957 (62.2%) with preserved ejection fraction. This prevalence remained constant from 2008 to 2019. Compared to patients with HF and reduced ejection fraction (HFREF) patients with HF-PEF are older, more are female, there is a higher prevalence of hypertensive and valvular aetiology, they have a profile of different comorbidities and worse functional status. A high proportion of patients receive disease-modifying treatment for IC-REF (renin-angiotensin-aldosterone system inhibitors and beta-blockers). The overall mortality after one-year follow-up was 24% and 30% in the HF-PEF and the HF-REF, respectively. In the multivariate analysis, the risk of death was higher in patients with HF-REF compared to HF-PEF (OR: 1.84; 95% CI: [1.43-2.36]). The length of hospital stay was also lower in the HF-PEF patients but there were no differences in re-hospitalizations. Conclusions: Sixty percent of patients in the RICA registry have preserved ejection fraction. These patients have a higher comorbidity burden and a worse functional status, but lower mortality compared with HF-REF patients. (c) 2020 Elsevier Espana, S.L.U. All rights reserved.ELSEVIER ESPANA SLU2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fisabio.portalinvestigacion.com/publicaciones/12026MEDICINA CLINICAISSN: 00257753ISSNe: 15788989reponame:r-FISABIO. Repositorio Institucional de Producción Científicainstname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)Inglésinfo:eu-repo/semantics/openAccessoai:fisabio.fundanetsuite.com:p120262026-06-11T12:45:17Z
dc.title.none.fl_str_mv Epidemiology of heart failure with preserved ejection fraction: Results from the RICA Registry
title Epidemiology of heart failure with preserved ejection fraction: Results from the RICA Registry
spellingShingle Epidemiology of heart failure with preserved ejection fraction: Results from the RICA Registry
Trullas, JC
Heart failure
Diastolic
Stroke volume
Epidemiology
title_short Epidemiology of heart failure with preserved ejection fraction: Results from the RICA Registry
title_full Epidemiology of heart failure with preserved ejection fraction: Results from the RICA Registry
title_fullStr Epidemiology of heart failure with preserved ejection fraction: Results from the RICA Registry
title_full_unstemmed Epidemiology of heart failure with preserved ejection fraction: Results from the RICA Registry
title_sort Epidemiology of heart failure with preserved ejection fraction: Results from the RICA Registry
dc.creator.none.fl_str_mv Trullas, JC
Perez-Calvo, JI
Conde-Martel, A
Iborra, PL
Pedreira, IS
Ormaechea, G
Rangel, LS
Franco, AG
Cepeda, JM
Montero-Perez-Barquer, M
representacion Investigadores
author Trullas, JC
author_facet Trullas, JC
Perez-Calvo, JI
Conde-Martel, A
Iborra, PL
Pedreira, IS
Ormaechea, G
Rangel, LS
Franco, AG
Cepeda, JM
Montero-Perez-Barquer, M
representacion Investigadores
author_role author
author2 Perez-Calvo, JI
Conde-Martel, A
Iborra, PL
Pedreira, IS
Ormaechea, G
Rangel, LS
Franco, AG
Cepeda, JM
Montero-Perez-Barquer, M
representacion Investigadores
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Heart failure
Diastolic
Stroke volume
Epidemiology
topic Heart failure
Diastolic
Stroke volume
Epidemiology
description Introduction and objectives: There is great interest in better characterizing patients with heart failure (HF) with preserved ejection fraction (HF-PEF). The objective of this study is to determine the prevalence, progression over time and to describe the clinical and epidemiological characteristics of patients with HF-PEF. Methods: From the National Registry of Heart Failure (RICA, prospective multicentre cohort study) we analysed patients consecutively admitted for HF in Internal Medicine wards over a period of 11 years (2008-2018). Results: 4752 patients were included, 2957 (62.2%) with preserved ejection fraction. This prevalence Introduction and objectives: There is great interest in better characterizing patients with heart failure (HF) with preserved ejection fraction (HF-PEF). The objective of this study is to determine the prevalence, progression over time and to describe the clinical and epidemiological characteristics of patients with HF-PEF. Methods: From the National Registry of Heart Failure (RICA, prospective multicentre cohort study) we analysed patients consecutively admitted for HF in Internal Medicine wards over a period of 11 years (2008-2018). Results: 4752 patients were included, 2957 (62.2%) with preserved ejection fraction. This prevalence remained constant from 2008 to 2019. Compared to patients with HF and reduced ejection fraction (HFREF) patients with HF-PEF are older, more are female, there is a higher prevalence of hypertensive and valvular aetiology, they have a profile of different comorbidities and worse functional status. A high proportion of patients receive disease-modifying treatment for IC-REF (renin-angiotensin-aldosterone system inhibitors and beta-blockers). The overall mortality after one-year follow-up was 24% and 30% in the HF-PEF and the HF-REF, respectively. In the multivariate analysis, the risk of death was higher in patients with HF-REF compared to HF-PEF (OR: 1.84; 95% CI: [1.43-2.36]). The length of hospital stay was also lower in the HF-PEF patients but there were no differences in re-hospitalizations. Conclusions: Sixty percent of patients in the RICA registry have preserved ejection fraction. These patients have a higher comorbidity burden and a worse functional status, but lower mortality compared with HF-REF patients. (c) 2020 Elsevier Espana, S.L.U. All rights reserved.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fisabio.portalinvestigacion.com/publicaciones/12026
url https://fisabio.portalinvestigacion.com/publicaciones/12026
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv ELSEVIER ESPANA SLU
publisher.none.fl_str_mv ELSEVIER ESPANA SLU
dc.source.none.fl_str_mv MEDICINA CLINICA
ISSN: 00257753
ISSNe: 15788989
reponame:r-FISABIO. Repositorio Institucional de Producción Científica
instname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
instname_str Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
reponame_str r-FISABIO. Repositorio Institucional de Producción Científica
collection r-FISABIO. Repositorio Institucional de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,81155

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