Replication data for: Activation of the PI3K/AKT/mTOR pathway decreases kidney Klotho

This dataset includes the files with data, graphs and statistics for the paper: Activation of the PI3K/AKT/mTOR pathway decreases kidney Klotho. It includes data of Klotho expression in vitro and in vivo after deleting PTEN or pharmacologically inhibit the pathway with Rapamycin. It also includes da...

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Detalles Bibliográficos
Autor: Valdivielso Revilla, José Manuel
Tipo de recurso: conjunto de datos
Fecha de publicación:2024
País:España
Institución:Consorci de Serveis Universitaris de Catalunya (CSUC)
Repositorio:CORA.Repositori de Dades de Recerca
OAI Identifier:oai:dnet:cora.rdr____::531e967283928c22f2b489b8a1aa2f79
Acceso en línea:https://doi.org/10.34810/DATA1515
Access Level:acceso abierto
Palabra clave:Medicine, Health and Life Sciences
Nephrology
Klotho Proteins
Descripción
Sumario:This dataset includes the files with data, graphs and statistics for the paper: Activation of the PI3K/AKT/mTOR pathway decreases kidney Klotho. It includes data of Klotho expression in vitro and in vivo after deleting PTEN or pharmacologically inhibit the pathway with Rapamycin. It also includes data on mineral metabolism parameters of mice with deletion of PTEN in the renal proximal tubules, animals with uninephrectomy and treated with rapamycin and animals with an experimental model of chronic kdney disase teated with the same drug.