Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.

Chaparro M; Garre A; Núñez Ortiz A; Diz-Lois Palomares MT; Rodríguez C; Riestra S; Vela M; Benítez JM; Fernández Salgado E; Sánchez Rodríguez E; Hernández V; Ferreiro-Iglesias R; Ponferrada Díaz Á; Barrio J; Huguet JM; Sicilia B; Martín-Arranz MD; Calvet X; Ginard D; Alonso-Abreu I; Fernández-Salazar L; Varela Trastoy P; Rivero M; Vera-Mendoza I; Vega P; Navarro P; Sierra M; Cabriada JL; Aguas M; Vicente R; Navarro-Llavat M; Echarri A; Gomollón F; Guerra Del Río E; Piñero C; Casanova MJ; Spicakova K; Ortiz de Zarate J; Torrella Cortés E; Gutiérrez A; Alonso-Galán H; Hernández-Martínez Á; Marrero JM; Lorente Poyatos R; Calafat M; Martí Romero L; Robledo P; Bosch O; Jiménez N; Esteve Comas M; Duque JM; Fuentes Coronel AM; Josefa Sampedro M; Sesé Abizanda E; Herreros Martínez B; Pozzati L; Fernández Rosáenz H; Crespo Suarez B; López Serrano P; Lucendo AJ; Muñoz Vicente M; Bermejo F; Ramírez Palanca JJ; Menacho M; Carmona A; Camargo R; Torra Alsina S; Maroto N; Nerín de la Puerta J; Castro E; Marín-Jiménez I; Botella B; Sapiña A; Cruz N; Forcelledo JLF; Bouhmidi A; Castaño-Milla C; Opio V; Nicolás I; Kutz M; Abraldes Bechiarelli A; Gordillo J; Ber Y; Torres Domínguez Y; Novella Durán MT; Rodríguez Mondéjar S; Martínez-Cerezo FJ; Kolle L; Sabat M; Ledezma C; Iyo E; Roncero Ó; Irisarri R; Lluis L; Blázquez Gómez I; Zapata EM; José Alcalá M; Martínez Pascual C; Montealegre M; Mata L; Monrobel A; Hernández Camba A; Hernández L; Tejada M; Mir A; Galve ML; Soler M; Hervías D; Gómez-Valero JA; Barreiro-de Acosta M; Rodríguez-Artalejo F; García-Esquinas E; Gisbert JP; On Behalf Of The EpidemIBD Study Group Of Geteccu

Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.

(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry....

Descripción completa

Detalles Bibliográficos
Autores:	Chaparro M, Garre A, Núñez Ortiz A, Diz-Lois Palomares MT, Rodríguez C, Riestra S, Vela M, Benítez JM, Fernández Salgado E, Sánchez Rodríguez E, Hernández V, Ferreiro-Iglesias R, Ponferrada Díaz Á, Barrio J, Huguet JM, Sicilia B, Martín-Arranz MD, Calvet X, Ginard D, Alonso-Abreu I, Fernández-Salazar L, Varela Trastoy P, Rivero M, Vera-Mendoza I, Vega P, Navarro P, Sierra M, Cabriada JL, Aguas M, Vicente R, Navarro-Llavat M, Echarri A, Gomollón F, Guerra Del Río E, Piñero C, Casanova MJ, Spicakova K, Ortiz de Zarate J, Torrella Cortés E, Gutiérrez A, Alonso-Galán H, Hernández-Martínez Á, Marrero JM, Lorente Poyatos R, Calafat M, Martí Romero L, Robledo P, Bosch O, Jiménez N, Esteve Comas M, Duque JM, Fuentes Coronel AM, Josefa Sampedro M, Sesé Abizanda E, Herreros Martínez B, Pozzati L, Fernández Rosáenz H, Crespo Suarez B, López Serrano P, Lucendo AJ, Muñoz Vicente M, Bermejo F, Ramírez Palanca JJ, Menacho M, Carmona A, Camargo R, Torra Alsina S, Maroto N, Nerín de la Puerta J, Castro E, Marín-Jiménez I, Botella B, Sapiña A, Cruz N, Forcelledo JLF, Bouhmidi A, Castaño-Milla C, Opio V, Nicolás I, Kutz M, Abraldes Bechiarelli A, Gordillo J, Ber Y, Torres Domínguez Y, Novella Durán MT, Rodríguez Mondéjar S, Martínez-Cerezo FJ, Kolle L, Sabat M, Ledezma C, Iyo E, Roncero Ó, Irisarri R, Lluis L, Blázquez Gómez I, Zapata EM, José Alcalá M, Martínez Pascual C, Montealegre M, Mata L, Monrobel A, Hernández Camba A, Hernández L, Tejada M, Mir A, Galve ML, Soler M, Hervías D, Gómez-Valero JA, Barreiro-de Acosta M, Rodríguez-Artalejo F, García-Esquinas E, Gisbert JP, On Behalf Of The EpidemIBD Study Group Of Geteccu
Tipo de recurso:	artículo
Estado:	Versión publicada
Fecha de publicación:	2021
País:	España
Institución:	Institut d'Investigació i Innovació Parc Taulí (I3PT)
Repositorio:	r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
OAI Identifier:	oai:i3pt.fundanetsuite.com:p1716
Acceso en línea:	https://i3pt.portalinvestigacion.com/publicaciones/1716
Access Level:	acceso abierto
Palabra clave:	Crohn’s disease, epidemiology, incidence, inflammatory bowel disease, ulcerative colitis

id	ES_d8a09f75adc40edf8ce7eb978ff9f41a
oai_identifier_str	oai:i3pt.fundanetsuite.com:p1716
network_acronym_str	ES
network_name_str	España
repository_id_str
spelling	Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.Chaparro MGarre ANúñez Ortiz ADiz-Lois Palomares MTRodríguez CRiestra SVela MBenítez JMFernández Salgado ESánchez Rodríguez EHernández VFerreiro-Iglesias RPonferrada Díaz ÁBarrio JHuguet JMSicilia BMartín-Arranz MDCalvet XGinard DAlonso-Abreu IFernández-Salazar LVarela Trastoy PRivero MVera-Mendoza IVega PNavarro PSierra MCabriada JLAguas MVicente RNavarro-Llavat MEcharri AGomollón FGuerra Del Río EPiñero CCasanova MJSpicakova KOrtiz de Zarate JTorrella Cortés EGutiérrez AAlonso-Galán HHernández-Martínez ÁMarrero JMLorente Poyatos RCalafat MMartí Romero LRobledo PBosch OJiménez NEsteve Comas MDuque JMFuentes Coronel AMJosefa Sampedro MSesé Abizanda EHerreros Martínez BPozzati LFernández Rosáenz HCrespo Suarez BLópez Serrano PLucendo AJMuñoz Vicente MBermejo FRamírez Palanca JJMenacho MCarmona ACamargo RTorra Alsina SMaroto NNerín de la Puerta JCastro EMarín-Jiménez IBotella BSapiña ACruz NForcelledo JLFBouhmidi ACastaño-Milla COpio VNicolás IKutz MAbraldes Bechiarelli AGordillo JBer YTorres Domínguez YNovella Durán MTRodríguez Mondéjar SMartínez-Cerezo FJKolle LSabat MLedezma CIyo ERoncero ÓIrisarri RLluis LBlázquez Gómez IZapata EMJosé Alcalá MMartínez Pascual CMontealegre MMata LMonrobel AHernández Camba AHernández LTejada MMir AGalve MLSoler MHervías DGómez-Valero JABarreiro-de Acosta MRodríguez-Artalejo FGarcía-Esquinas EGisbert JPOn Behalf Of The EpidemIBD Study Group Of GeteccuCrohn’s disease, epidemiology, incidence, inflammatory bowel disease, ulcerative colitis(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery.MDPI2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://i3pt.portalinvestigacion.com/publicaciones/1716Journal of Clinical MedicineISSN: 20770383reponame:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulíinstname:Institut d'Investigació i Innovació Parc Taulí (I3PT)Inglésinfo:eu-repo/semantics/openAccessoai:i3pt.fundanetsuite.com:p17162026-06-21T15:30:37Z
dc.title.none.fl_str_mv	Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.
title	Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.
spellingShingle	Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. Chaparro M Crohn’s disease, epidemiology, incidence, inflammatory bowel disease, ulcerative colitis
title_short	Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.
title_full	Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.
title_fullStr	Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.
title_full_unstemmed	Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.
title_sort	Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.
dc.creator.none.fl_str_mv	Chaparro M Garre A Núñez Ortiz A Diz-Lois Palomares MT Rodríguez C Riestra S Vela M Benítez JM Fernández Salgado E Sánchez Rodríguez E Hernández V Ferreiro-Iglesias R Ponferrada Díaz Á Barrio J Huguet JM Sicilia B Martín-Arranz MD Calvet X Ginard D Alonso-Abreu I Fernández-Salazar L Varela Trastoy P Rivero M Vera-Mendoza I Vega P Navarro P Sierra M Cabriada JL Aguas M Vicente R Navarro-Llavat M Echarri A Gomollón F Guerra Del Río E Piñero C Casanova MJ Spicakova K Ortiz de Zarate J Torrella Cortés E Gutiérrez A Alonso-Galán H Hernández-Martínez Á Marrero JM Lorente Poyatos R Calafat M Martí Romero L Robledo P Bosch O Jiménez N Esteve Comas M Duque JM Fuentes Coronel AM Josefa Sampedro M Sesé Abizanda E Herreros Martínez B Pozzati L Fernández Rosáenz H Crespo Suarez B López Serrano P Lucendo AJ Muñoz Vicente M Bermejo F Ramírez Palanca JJ Menacho M Carmona A Camargo R Torra Alsina S Maroto N Nerín de la Puerta J Castro E Marín-Jiménez I Botella B Sapiña A Cruz N Forcelledo JLF Bouhmidi A Castaño-Milla C Opio V Nicolás I Kutz M Abraldes Bechiarelli A Gordillo J Ber Y Torres Domínguez Y Novella Durán MT Rodríguez Mondéjar S Martínez-Cerezo FJ Kolle L Sabat M Ledezma C Iyo E Roncero Ó Irisarri R Lluis L Blázquez Gómez I Zapata EM José Alcalá M Martínez Pascual C Montealegre M Mata L Monrobel A Hernández Camba A Hernández L Tejada M Mir A Galve ML Soler M Hervías D Gómez-Valero JA Barreiro-de Acosta M Rodríguez-Artalejo F García-Esquinas E Gisbert JP On Behalf Of The EpidemIBD Study Group Of Geteccu
author	Chaparro M
author_facet	Chaparro M Garre A Núñez Ortiz A Diz-Lois Palomares MT Rodríguez C Riestra S Vela M Benítez JM Fernández Salgado E Sánchez Rodríguez E Hernández V Ferreiro-Iglesias R Ponferrada Díaz Á Barrio J Huguet JM Sicilia B Martín-Arranz MD Calvet X Ginard D Alonso-Abreu I Fernández-Salazar L Varela Trastoy P Rivero M Vera-Mendoza I Vega P Navarro P Sierra M Cabriada JL Aguas M Vicente R Navarro-Llavat M Echarri A Gomollón F Guerra Del Río E Piñero C Casanova MJ Spicakova K Ortiz de Zarate J Torrella Cortés E Gutiérrez A Alonso-Galán H Hernández-Martínez Á Marrero JM Lorente Poyatos R Calafat M Martí Romero L Robledo P Bosch O Jiménez N Esteve Comas M Duque JM Fuentes Coronel AM Josefa Sampedro M Sesé Abizanda E Herreros Martínez B Pozzati L Fernández Rosáenz H Crespo Suarez B López Serrano P Lucendo AJ Muñoz Vicente M Bermejo F Ramírez Palanca JJ Menacho M Carmona A Camargo R Torra Alsina S Maroto N Nerín de la Puerta J Castro E Marín-Jiménez I Botella B Sapiña A Cruz N Forcelledo JLF Bouhmidi A Castaño-Milla C Opio V Nicolás I Kutz M Abraldes Bechiarelli A Gordillo J Ber Y Torres Domínguez Y Novella Durán MT Rodríguez Mondéjar S Martínez-Cerezo FJ Kolle L Sabat M Ledezma C Iyo E Roncero Ó Irisarri R Lluis L Blázquez Gómez I Zapata EM José Alcalá M Martínez Pascual C Montealegre M Mata L Monrobel A Hernández Camba A Hernández L Tejada M Mir A Galve ML Soler M Hervías D Gómez-Valero JA Barreiro-de Acosta M Rodríguez-Artalejo F García-Esquinas E Gisbert JP On Behalf Of The EpidemIBD Study Group Of Geteccu
author_role	author
author2	Garre A Núñez Ortiz A Diz-Lois Palomares MT Rodríguez C Riestra S Vela M Benítez JM Fernández Salgado E Sánchez Rodríguez E Hernández V Ferreiro-Iglesias R Ponferrada Díaz Á Barrio J Huguet JM Sicilia B Martín-Arranz MD Calvet X Ginard D Alonso-Abreu I Fernández-Salazar L Varela Trastoy P Rivero M Vera-Mendoza I Vega P Navarro P Sierra M Cabriada JL Aguas M Vicente R Navarro-Llavat M Echarri A Gomollón F Guerra Del Río E Piñero C Casanova MJ Spicakova K Ortiz de Zarate J Torrella Cortés E Gutiérrez A Alonso-Galán H Hernández-Martínez Á Marrero JM Lorente Poyatos R Calafat M Martí Romero L Robledo P Bosch O Jiménez N Esteve Comas M Duque JM Fuentes Coronel AM Josefa Sampedro M Sesé Abizanda E Herreros Martínez B Pozzati L Fernández Rosáenz H Crespo Suarez B López Serrano P Lucendo AJ Muñoz Vicente M Bermejo F Ramírez Palanca JJ Menacho M Carmona A Camargo R Torra Alsina S Maroto N Nerín de la Puerta J Castro E Marín-Jiménez I Botella B Sapiña A Cruz N Forcelledo JLF Bouhmidi A Castaño-Milla C Opio V Nicolás I Kutz M Abraldes Bechiarelli A Gordillo J Ber Y Torres Domínguez Y Novella Durán MT Rodríguez Mondéjar S Martínez-Cerezo FJ Kolle L Sabat M Ledezma C Iyo E Roncero Ó Irisarri R Lluis L Blázquez Gómez I Zapata EM José Alcalá M Martínez Pascual C Montealegre M Mata L Monrobel A Hernández Camba A Hernández L Tejada M Mir A Galve ML Soler M Hervías D Gómez-Valero JA Barreiro-de Acosta M Rodríguez-Artalejo F García-Esquinas E Gisbert JP On Behalf Of The EpidemIBD Study Group Of Geteccu
author2_role	author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author
dc.subject.none.fl_str_mv	Crohn’s disease, epidemiology, incidence, inflammatory bowel disease, ulcerative colitis
topic	Crohn’s disease, epidemiology, incidence, inflammatory bowel disease, ulcerative colitis
description	(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery.
publishDate	2021
dc.date.none.fl_str_mv	2021
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	https://i3pt.portalinvestigacion.com/publicaciones/1716
url	https://i3pt.portalinvestigacion.com/publicaciones/1716
dc.language.none.fl_str_mv	Inglés
language_invalid_str_mv	Inglés
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.publisher.none.fl_str_mv	MDPI
publisher.none.fl_str_mv	MDPI
dc.source.none.fl_str_mv	Journal of Clinical Medicine ISSN: 20770383 reponame:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí instname:Institut d'Investigació i Innovació Parc Taulí (I3PT)
instname_str	Institut d'Investigació i Innovació Parc Taulí (I3PT)
reponame_str	r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
collection	r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_	1869421189970001920
score	15,81155

Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.

Similares en LA Referencia