Design and implementation of a next-generation sequencing test for the fast and cost-effective SARS-CoV-2 differantial diagnosis and variant detection
In the beginning of 2020 the WHO declared a pandemic that was initiated by the outbreak of a new virus named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that quickly spread globally, challenging our society and turning it upside down in ways we did not anticipate. The continuous...
| Autor: | |
|---|---|
| Tipo de recurso: | tesis doctoral |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | CBUC, CESCA |
| Repositorio: | TDR. Tesis Doctorales en Red |
| OAI Identifier: | oai:www.tdx.cat:10803/692226 |
| Acceso en línea: | http://hdl.handle.net/10803/692226 |
| Access Level: | acceso abierto |
| Palabra clave: | Pandemic SARS-CoV-2 NGS RNA sequencing Differential diagnosis Respiratory viruses Pandemia Diagnóstico diferencial Virus respiratorios 578 |
| Sumario: | In the beginning of 2020 the WHO declared a pandemic that was initiated by the outbreak of a new virus named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that quickly spread globally, challenging our society and turning it upside down in ways we did not anticipate. The continuous emergence of new SARS-CoV-2 variants together with the compatibility of the coronavirus disease (COVID-19) symptomatology with other viral respiratory infections revealed the need of developing more specific tools than the methods that were widely implemented throughout the pandemic. This thesis presents a novel next generation sequencing (NGS) based testing strategy that aims to differentially diagnose SARS-CoV-2 virus and its variants, as well as other respiratory viruses in order to overcome the limitations of the existing testing methods. |
|---|