Screening for Inflammatory Chronic Arthritis in Hidradenitis Suppurativa with Psoriatic Arthritis Uncluttered Screening Evaluation (PURE) Questionnaire

Introduction: Considering the growing recognition of the association between hidradenitis suppurativa (HS) and spondyloarthritis, this study addresses a gap in clinical practice in HS consultation: the absence of a validated arthritis screening tool. Methods: Drawing on interdisciplinary collaborati...

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Detalles Bibliográficos
Autores: Garbayo-Salmons, P, Moreno, M, Rodrigo-Parés, A, Saus, E, Exposito-Serrano, V, Ribera, M, Calvet, J
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Institut d'Investigació i Innovació Parc Taulí (I3PT)
Repositorio:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
OAI Identifier:oai:i3pt.fundanetsuite.com:p6554
Acceso en línea:https://i3pt.portalinvestigacion.com/publicaciones/6554
https://www.scopus.com/inward/record.uri?eid=2-s2.0-105011940414&doi=10.1159%2F000547045&partnerID=40&md5=bbe04cdc61513ee342d3e76a1c7c1e62
Access Level:acceso abierto
Palabra clave:Hidradenitis suppurativa
Arthritis
Spondyloarthritis
Screening
Descripción
Sumario:Introduction: Considering the growing recognition of the association between hidradenitis suppurativa (HS) and spondyloarthritis, this study addresses a gap in clinical practice in HS consultation: the absence of a validated arthritis screening tool. Methods: Drawing on interdisciplinary collaboration between dermatology and rheumatology, we assayed a modified version of the PURE-4 tool: patient and dermatologist Psoriatic Arthritis Uncluttered Screening Evaluation-5 (p- and dPURE-5), adapted to reflect clinical features relevant to this population. Results: Of 214 HS patients, 125 (58.4%) were male, with a median age of 42 years (IQR 30-49). Buttock involvement was observed in 64 patients (29.9%) and was more common in males (35.7%) than in females (21.6%) (p = 0.26). Of the 214 patients, 82 (38.3%) answered negatively to all questions, while 118 (55.6%) answered positively to at least one question in the pPURE-5 but were later dismissed by the trained dermatologist after a more detailed interview. Finally, 14 patients (6.5%) were referred to Rheumatology due to a positive dPURE-5. Of these, 2 (14.3%) were diagnosed with inflammatory chronic arthritis, yielding a positive predictive value of 14.3%. Conclusion: To conclude, the PURE-5 questionnaire appeared valuable for guiding anamnesis and facilitating rheumatology referrals. Even so, there is still a need for new and validated screening tools for detecting arthritis in the HS population.