Gluteal Hidradenitis Suppurativa: Analysis of 83 Patients
Background: In 2013, Canoui-Poitrine et al. identified three hidradenitis suppurativa (HS) phenotypes by a latent class (LC) analysis, based on anatomical sites of involvement. Objective: To improve the classification of the gluteal phenotype (LC3) patients given their diverse lesion types and diffe...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Institut d'Investigació i Innovació Parc Taulí (I3PT) |
| Repositorio: | r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí |
| OAI Identifier: | oai:i3pt.fundanetsuite.com:p4495 |
| Acceso en línea: | https://i3pt.portalinvestigacion.com/publicaciones/4495 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85174742268&doi=10.1016%2fj.ad.2023.09.021&partnerID=40&md5=a1e1b093eba43ac31dd4f1569ab01642 |
| Access Level: | acceso abierto |
| Palabra clave: | Acne inversa Hidradenitis suppurativa Hidradenitis suppurativa classification Hidradenitis suppurativa phenotypes Inflammation |
| Sumario: | Background: In 2013, Canoui-Poitrine et al. identified three hidradenitis suppurativa (HS) phenotypes by a latent class (LC) analysis, based on anatomical sites of involvement. Objective: To improve the classification of the gluteal phenotype (LC3) patients given their diverse lesion types and differences in clinical profile. Material and methods: We designed a bicentric study gathering all LC3 patients (n = 83) from two hospitals. We conducted a two-step cluster analysis among them and also compared their characteristics with the rest of the HS patients (n = 661). Results: Compared with global HS series, LC3 patients were more frequently non-obese men, with smoking habit, an associated arthropathy, and a more frequent history of pilonidal sinus. The analysis of LC3 patients yielded two clusters: cluster 1 (38.3%) included elderly female patients, with later diagnosis of the disease and more sinus tracts; cluster 2 (61.7%) encompassed more men with earlier disease onset and more nodules and folliculitis lesions. Limitations: The study's limitations include its retrospective nature, bicentric design, and small sample size. Conclusion: The heterogeneous clinical presentation of HS makes it essential to have a good classification of the patients. Gluteal phenotype could actually be classified into two “subphenotypes” with a different clinical profiles and management. © 2023 AEDV |
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