DisProt in 2022

The Database of Intrinsically Disordered Proteins (DisProt, URL: ) is the major repository of manually curated annotations of intrinsically disordered proteins and regions from the literature. We report here recent updates of DisProt version 9, including a restyled web interface, refactored Intrinsi...

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Detalles Bibliográficos
Autores: Quaglia, Federica|||0000-0002-0341-4888, Mészáros, Bálint|||0000-0003-0919-4449, Salladini, Edoardo|||0000-0002-5152-5953, Hatos, András|||0000-0001-9224-9820, Pancsa, Rita|||0000-0003-0849-9312, Chemes, Lucía Beatriz|||0000-0003-0192-9906, Pajkos, Mátyás|||0000-0001-5791-9825, Lazar, Tamas|||0000-0001-7496-6711, Peña Díaz, Samuel|||0000-0002-2902-823X, Santos Suárez, Jaime|||0000-0001-9045-7765, Ács, Veronika|||0000-0001-6260-7287, Farahi, Nazanin|||0000-0002-6834-8578, Fichó, Erzsébet|||0000-0002-3965-8438, Aspromonte, Maria Cristina|||0000-0002-4937-6952, Bassot, Claudio|||0000-0001-7161-9028, Chasapi, Anastasia|||0000-0003-1986-5007, Davey, Norman E.|||0000-0001-6988-4850, Davidović, Radoslav|||0000-0002-6097-6203, Dobson, Laszlo|||0000-0003-2765-3872, Elofsson, Arne|||0000-0002-7115-9751, Erdős, Gábor|||0000-0001-6218-5192, Gaudet, Pascale|||0000-0003-1813-6857, Giglio, Michelle|||0000-0001-7628-5565, Glavina, Juliana|||0000-0001-6336-1290, Iserte, Javier|||0000-0003-0056-1177, Iglesias, Valentin|||0000-0002-6133-0869, Kálmán, Zsófia|||0000-0003-4634-0433, Lambrughi, Matteo|||0000-0002-0894-8627, Leonardi, Emanuela|||0000-0001-8486-8461, Longhi, Sonia|||0000-0002-6829-6771, Macedo-Ribeiro, Sandra|||0000-0002-7698-1170, Maiani, Emiliano|||0000-0003-1432-5394, Marchetti, Julia|||0000-0002-2886-3647, Marino-Buslje, Cristina|||0000-0002-6564-1920, Mészáros, Attila|||0000-0002-4578-4879, Monzon, Alexander Miguel|||0000-0003-0362-8218, Minervini, Giovanni|||0000-0001-7013-5785, Nadendla, Suvarna|||0000-0003-3643-281X, Nilsson, Juliet F.|||0000-0003-4203-5263, Novotný, Marian|||0000-0001-8788-3202, Ouzounis, Christos|||0000-0002-0086-8657, Palopoli, Nicolás|||0000-0001-7925-6436, Papaleo, Elena|||0000-0002-7376-5894, Pereira, Pedro José Barbosa|||0000-0003-0969-5438, Pozzati, Gabriele|||0000-0002-4303-9939, Promponas, Vasilis J.|||0000-0003-3352-4831, Pujols Pujol, Jordi|||0000-0001-9424-5866, Sanchez Rocha, Alma Carolina|||0000-0001-7395-9173, Salas, Martin|||0000-0001-6352-1282, Sawicki, Luciana Rodriguez|||0000-0001-5782-6573, Schad, Eva|||0000-0002-3006-2910, Shenoy, Aditi|||0000-0001-7748-2501, Szaniszló, Tamás|||0000-0002-3130-9284, Tsirigos, Konstantinos D.|||0000-0001-5280-1107, Veljkovic, Nevena|||0000-0001-6562-5800, Parisi, Gustavo|||0000-0001-7444-1624, Ventura, Salvador|||0000-0002-9652-6351, Dosztányi, Zsuzsanna|||0000-0002-3624-5937, Tompa, Peter|||0000-0001-8042-9939, Tosatto, Silvio|||0000-0003-4525-7793, Piovesan, Damiano|||0000-0001-8210-2390
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:303324
Acceso en línea:https://ddd.uab.cat/record/303324
https://dx.doi.org/urn:doi:10.1093/nar/gkab1082
Access Level:acceso abierto
Descripción
Sumario:The Database of Intrinsically Disordered Proteins (DisProt, URL: ) is the major repository of manually curated annotations of intrinsically disordered proteins and regions from the literature. We report here recent updates of DisProt version 9, including a restyled web interface, refactored Intrinsically Disordered Proteins Ontology (IDPO), improvements in the curation process and significant content growth of around 30%. Higher quality and consistency of annotations is provided by a newly implemented reviewing process and training of curators. The increased curation capacity is fostered by the integration of DisProt with APICURON, a dedicated resource for the proper attribution and recognition of biocuration efforts. Better interoperability is provided through the adoption of the Minimum Information About Disorder (MIADE) standard, an active collaboration with the Gene Ontology (GO) and Evidence and Conclusion Ontology (ECO) consortia and the support of the ELIXIR infrastructure.

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