Association of fecal and serum microRNA profiles with gastrointestinal cancer and chronic inflammatory enteropathy in dogs

[Background] Reliable biomarkers to differentiate gastrointestinal cancer (GIC) from chronic inflammatory enteropathy (CIE) in dogs are needed. Fecal and serum microRNAs (miRNAs) have been proposed as diagnostic and prognostic markers of GI disease in humans and dogs.

Bibliographic Details
Authors: Lyngby, Janne G., Gòdia, Marta, Brogaard, Louise, Kristensen, Annemarie T., Fredholm, Merete, Skancke, Ellen, Morris, Joanna, Dupont, Nana, Salavati, Silke, Argyle, David, Sánchez, Armand, Bjørnvad, Charlotte R., Graarup-Hansen, Kasper, Spohr, Anette, Cirera, Susanna, Nielsen, Lise Nikolic
Format: article
Status:Published version
Publication Date:2022
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/297022
Online Access:http://hdl.handle.net/10261/297022
Access Level:Open access
Keyword:Biomarker
CIE
MiRNA qPCR
Neoplasia
RT-qPCR
Small RNA sequencing
Description
Summary:[Background] Reliable biomarkers to differentiate gastrointestinal cancer (GIC) from chronic inflammatory enteropathy (CIE) in dogs are needed. Fecal and serum microRNAs (miRNAs) have been proposed as diagnostic and prognostic markers of GI disease in humans and dogs.

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