Association of fecal and serum microRNA profiles with gastrointestinal cancer and chronic inflammatory enteropathy in dogs

[Background] Reliable biomarkers to differentiate gastrointestinal cancer (GIC) from chronic inflammatory enteropathy (CIE) in dogs are needed. Fecal and serum microRNAs (miRNAs) have been proposed as diagnostic and prognostic markers of GI disease in humans and dogs.

Detalles Bibliográficos
Autores: Lyngby, Janne G., Gòdia, Marta, Brogaard, Louise, Kristensen, Annemarie T., Fredholm, Merete, Skancke, Ellen, Morris, Joanna, Dupont, Nana, Salavati, Silke, Argyle, David, Sánchez, Armand, Bjørnvad, Charlotte R., Graarup-Hansen, Kasper, Spohr, Anette, Cirera, Susanna, Nielsen, Lise Nikolic
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/297022
Acceso en línea:http://hdl.handle.net/10261/297022
Access Level:acceso abierto
Palabra clave:Biomarker
CIE
MiRNA qPCR
Neoplasia
RT-qPCR
Small RNA sequencing
Descripción
Sumario:[Background] Reliable biomarkers to differentiate gastrointestinal cancer (GIC) from chronic inflammatory enteropathy (CIE) in dogs are needed. Fecal and serum microRNAs (miRNAs) have been proposed as diagnostic and prognostic markers of GI disease in humans and dogs.

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