Binge Drinking and Risk of Breast Cancer: Results from the SUN (‘Seguimiento Universidad de Navarra’) Project

Alcohol intake is associated with the risk of breast cancer. Different patterns of alcoholdrinking may have different effects on breast cancer even when keeping constant the total amount of alcohol consumed. We aimed to assess the association between binge drinking and breast cancer risk. The SUN Pr...

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Detalles Bibliográficos
Autores: Sanchez-Bayona, R. (Rodrigo)|||/items/87f95f8a-7474-40d8-9ac8-14ee3c1cc6ba, Gea, A. (Alfredo)|||/items/0fc6850b-e4e0-4795-960d-db184cd1385f, Gardeazabal, I. (Itziar)|||/items/0a92ab60-57bb-4494-9dee-e34e115c2688, Romanos-Nanclares, A. (Andrea)|||/items/11d87df0-9d0e-4a4b-bffe-b71ef4c6e5c0, Martínez-González, M.A. (Miguel Ángel)|||/items/8b591471-4165-4697-8534-cfa0ad5eb1b7, Bes-Rastrollo, M. (Maira)|||/items/d46c05fd-209a-4259-90c6-07202d4c72af, Santisteban-Eslava, M. (Marta)|||/items/563d2cef-8a22-4110-97f4-8e16eac15419, Toledo-Atucha, E. (Estefanía)|||/items/a67de95c-b88e-4c23-8fb9-6482b0f9fba0
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/65576
Acceso en línea:https://hdl.handle.net/10171/65576
Access Level:acceso abierto
Palabra clave:Breast cancer
Alcohol
binge drinking
Cohort
Descripción
Sumario:Alcohol intake is associated with the risk of breast cancer. Different patterns of alcoholdrinking may have different effects on breast cancer even when keeping constant the total amount of alcohol consumed. We aimed to assess the association between binge drinking and breast cancer risk. The SUN Project is a Spanish dynamic prospective cohort of university graduates initiated in 1999. In the 556-item lifestyle baseline questionnaire a validated food-frequency questionnaire was embedded. Participants completed biennial follow-up questionnaires. Cox regression models were used to estimate the hazard ratio (HR) for breast cancer associated with the exposure to binge drinking. A stratified analysis was performed according to menopausal status. We included 9577 women (mean age = 34 years, SD = 10 years), with a median follow-up of 11.8 years. Among 104,932 women-years of follow-up, we confirmed 88 incident cases of breast cancer. Women in the binge drinking group showed a higher risk of breast cancer (HR = 1.76; 95% CI: 1.03–2.99) compared to women in the non-binge drinking category. In the stratified analysis, a 2-fold higher risk for premenopausal breast cancer was associated with binge drinking habit (HR = 2.06; 95% CI: 1.11–3.82). This study adds new evidence on the association of binge drinking with breast cancer risk.

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